Development of an all-in-one PCPS system

The present paper deals with development of an all-in-one PCPS (Percutaneous Cardio Pulmonary Support) system. The system consists of a pump-oxygenator unit and pump controller. The pump-oxygenator unit contains centrifugal pump and extracapillary flow type membrane oxygenator (0.8 m2) in one compact body. Dimensions of the pump-oxygenator unit are as follows: length: 250 mm; diameter: 90 mm; weight: 1 kg. The unit has priming volume of 250 ml. The in-vitro tests (gas exchange, fluid dynamic performance, hemolysis) and an ex-vivo test was conducted. The results are as follows : 1. Fluid dynamic: The system products 1.6-3.8 l/min of flow against 100 mmHg of outlet pressure at a rotation speed of 2 500 to 3 500 rpm. 2. Hemolysis: The increase rate of plasma free hemoglobin was 22 mg&middotdl-1/h with the PCPS system. 3. Gas exchange: O2 transfer rate of the system was 180 ml/min and CO2 transfer rate was 120 ml/min (V/Q=1) at a blood flow rate 3 l/min. 4. Ex-vivo test: The device was operable. In conclusion, the system is considered applicable to cardio pulmonary support.