Recent Advances in Screening and Separating Active Components From Natural Products Based on High-Speed Countercurrent Chromatography

被引:0
|
作者
Wang, Xing-Cui [1 ,2 ,3 ]
Huang, Xin-Yi [1 ,2 ,3 ]
Zhang, Fu-Xin [1 ,2 ,3 ]
Muhire, Jules [1 ,2 ,3 ]
Di, Duo-Long [1 ,2 ,3 ]
Hai, Jun [1 ,2 ,3 ]
Pei, Dong [1 ,2 ,4 ]
机构
[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, CAS Key Lab Chem Northwestern Plant Resources, Lanzhou, Peoples R China
[2] Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou, Peoples R China
[3] Univ Chinese Acad Sci, Chem Dept, Beijing, Peoples R China
[4] Yunnan Ol Hlth Ind Innovat Res & Dev Co Ltd, Res Dept, Lijiang, Peoples R China
关键词
active compounds; high-speed countercurrent chromatography; natural products; post-column activity assay; pre-column activity assay; ULTRAFILTRATION LIQUID-CHROMATOGRAPHY; XANTHINE-OXIDASE INHIBITORS; POTENTIAL ALPHA-GLUCOSIDASE; TARGET-GUIDED ISOLATION; PREPARATIVE SEPARATION; BIOACTIVE COMPOUNDS; TYROSINASE INHIBITORS; ANTIOXIDANT ACTIVITY; MASS-SPECTROMETRY; PURIFICATION;
D O I
10.1002/jssc.70051
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Natural products play a vital role in human health because people find that they can reduce the incidence of many diseases, such as cancer and cardiovascular diseases. Therefore, researchers have developed many effective techniques for screening and separating active compounds from natural products. High-speed countercurrent chromatography is a unique unsupported liquid-liquid chromatography technology that has been widely used in the separation of natural products. In this paper, the research progress of screening and separating active components from natural products by combining high-speed countercurrent chromatography technology with other technologies is reviewed from two aspects: pre-column activity assay and post-column activity assay. The purpose of this paper is to provide some theoretical support for the screening and separation of natural active compounds by high-speed countercurrent chromatography. I hope that the contents summarized in this paper can provide more basis for the development of screening and separation of natural active compounds to realize large-scale preparation.
引用
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页数:16
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