A 10 W-peak 3.5 GHz LDMOS (lateral diffused MOSFET) power amplifier is designed according to the 802.16e WiMAX specification. The load-pull technique is used in decision of the best input/output impedances of the power transistor. The simulated values are in agreement with the experimental results. A method based on memory effect minimization and indirect learning is proposed and applied successfully to the behavioral modeling and digital predistortion of the implemented power amplifier. The workbench of multi-carrier signal generation and collection is also constructed. The experimental results show that a specification of -47.5 dBc, with an improvement of 14 dB, can be achieved for the power amplifier characterized by a Hammerstein model with only seven coefficients, driven by three-carrier W-CDMA wideband signal with an average output power of 30 dBm. Compared with conventional digital predistortion technique, the computational complexity can be reduced while high performance is maintained when the proposed method is adopted, which shows its promising application.