High altitude Relieves transmission risks of COVID-19 through meteorological and environmental factors: Evidence from China

被引:20
|
作者
Song P. [1 ]
Han H. [1 ]
Feng H. [1 ]
Hui Y. [1 ]
Zhou T. [1 ]
Meng W. [2 ]
Yan J. [2 ]
Li J. [2 ]
Fang Y. [3 ]
Liu P. [2 ]
Li X. [2 ]
Li X. [2 ]
机构
[1] Gansu Key Laboratory of Biomonitoring and Bioremediation for Environmental Pollution, School of Life Sciences, Lanzhou University, Tianshui South Road #222, Gansu, Lanzhou
[2] Key Laboratory for Biological Therapy and Regenerative Medicine Transformation Gansu Province, Lanzhou
[3] State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai
来源
Environmental Research | 2022年 / 212卷
基金
中国国家自然科学基金;
关键词
Altitude; COVID-19; Environmental factors; Mediating effect model; Transmission mechanism;
D O I
10.1016/j.envres.2022.113214
中图分类号
学科分类号
摘要
Existing studies reported higher altitudes reduce the COVID-19 infection rate in the United States, Colombia, and Peru. However, the underlying reasons for this phenomenon remain unclear. In this study, regression analysis and mediating effect model were used in a combination to explore the altitudes relation with the pattern of transmission under their correlation factors. The preliminary linear regression analysis indicated a negative correlation between altitudes and COVID-19 infection in China. In contrast to environmental factors from low-altitude regions (<1500 m), high-altitude regions (>1500 m) exhibited lower PM2.5, average temperature (AT), and mobility, accompanied by high SO2 and absolute humidity (AH). Non-linear regression analysis further revealed that COVID-19 confirmed cases had a positive correlation with mobility, AH, and AT, whereas negatively correlated with SO2, CO, and DTR. Subsequent mediating effect model with altitude-correlated factors, such as mobility, AT, AH, DTR and SO2, suffice to discriminate the COVID-19 infection rate between low- and high-altitude regions. The mentioned evidence advance our understanding of the altitude-mediated COVID-19 transmission mechanism. © 2022 Elsevier Inc.
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