Thermo-responsive gels: Biodegradable hydrogels from enantiomeric copolymers of poly(lactide) and poly(ethylene glycol)

被引:0
|
作者
Fujiwara, Tomoko [1 ]
机构
[1] Department of Chemistry, University of Memphis, 213 Smith Chemistry Bldg., Memphis, TN 38152, United States
来源
ACS Symposium Series | 2012年 / 1114卷
关键词
Biodegradable hydrogels - Bioresorbable polymers - Injectable biomaterials - Polymer designs - Stereocomplexation - Structures and properties - Temperature changes - Thermo-responsive;
D O I
10.1021/bk-2012-1114.ch017
中图分类号
学科分类号
摘要
Hydrogels responding to temperature changes are used for injectable biomaterials with many potential applications. Specifically, biocompatible hydrogels that can be safely injected without surgery and sustained/ disintegrated in a controlled manner are of interest. Poly(lactide), PLA, is the most studied and utilized bioresorbable polymer, and its block copolymers provide a great variety of structures and properties. Hydrogels utilizing stereocomplexation of the enantiomeric PLAs offer new polymer design and properties and expand their applications. © 2012 American Chemical Society.
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页码:287 / 311
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