[1] Department of Genomics and Computational Biology, University of Massachusetts, Chan Medical School, Worcester,MA,01605, United States
[2] Department of Mathematics, University of Maryland, College Park,MD,20742, United States
[3] Institute for Health Computing, University of Maryland, North Bethesda,MD,20852, United States
[4] School of Public Health, Tianjin Medical University, Tianjin,300070, China
[5] Broad Institute of MIT and Harvard, Cambridge,MA,02142, United States
[6] Department of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong