Deoxygenative alkynylation of amides via C 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 O bond cleavage

被引：0

作者：

Chen, Lan ^{[1
]}

Zhou, Wei ^{[1
]}

Zhang, Jianwen ^{[1
]}

Ding, Yimin ^{[1
]}

Szostak, Michal ^{[2
]}

Liu, Chengwei ^{[1
]}

机构：

[1] Department of Chemistry, Shanghai University, 99 Shangda Road, Shanghai,200444, China

[2] Department of Chemistry, Rutgers University, 73 Warren Street, Newark,NJ,07102, United States

来源：

Chemical Communications | 2024年 / 60卷 / 64期

关键词：

Amines - Rare earths - Transition metal compounds - Transition metals;

D O I：

10.1039/d4cc02316a

中图分类号：

学科分类号：

摘要：

A novel deoxygenative alkynylation of amides promoted by a synergistic action of a divalent rare-earth element and a transition metal has been developed. In this method, α-alkynyl substituted amines are synthesized from unactivated amides and alkynes in a single transformation. Broad substrate scope and excellent selectivity for C O cleavage has been demonstrated. This approach represents a general method for the construction of versatile α-alkynyl substituted amines from unactivated amide bonds. © 2024 The Royal Society of Chemistry.

引用

页码：8454 / 8457

共 11 条

[1] The B 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 C bond: some recent developments
Chen C.
Kehr G.
Erker G.
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Lough A.
Qu Z.-W.
Grimme S.
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[3] Ring expansion reactions of P 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 O-containing molecules
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Lynam J.M.
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[4] The contrasting reactivity of trans- vs. cis-azobenzenes (ArN 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 NAr) with benzynes
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[5] A novel three-component coupling reaction of aryne, C 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 N derivatives, and acrylonitrile
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Cai W.
Yu L.
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Song C.
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[6] Formation and evolution of C-C, C-O, C 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 O and C-N bonds in chemical reactions of prebiotic interest
Arias A.
Gómez S.
Rojas-Valencia N.
Núñez-Zarur F.
Cappelli C.
Murillo-López J.A.
Restrepo A.
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[7] Gas-phase synthesis of [O 00000000 00000000 00000000 00000000 11111111 00000000 11111111 00000000 00000000 00000000 U-X]+ (X = Cl, Br and I) from a UO22+ precursor using ion-molecule reactions and an [O U 00000000000000000 00000000000000000 00000000000000000 01111111111111110 00000000000000000 01111111111111110 00000000000000000 01111111111111110 00000000000000000 00000000000000000 00000000000000000 CH]+ intermediate
Terhorst J.
Lenze S.
Metzler L.
Fry A.N.
Ihabi A.
Corcovilos T.A.
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[8] 00000000X. Strategies and issues of the post-phoptography
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