Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance

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作者
Su, Yapeng [1 ,2 ]
Bintz, Marcus [3 ]
Yang, Yezi [3 ]
Robert, Lidia [4 ]
Ng, Alphonsus H. C. [1 ,2 ]
Liud, Victoria [2 ]
Ribas, Antoni [3 ,4 ,5 ,6 ]
Heath, James R. [1 ,2 ,6 ]
Wei, Wei [1 ,3 ,6 ]
机构
[1] Institute for Systems Biology, Seattle,WA, United States
[2] Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena,CA, United States
[3] Department of Molecular and Medical Pharmacology, University of California – Los Angeles, Los Angeles,CA, United States
[4] Department of Medicine, University of California – Los Angeles, Los Angeles,CA, United States
[5] Department of Surgery, Division of Surgical-Oncology, University of California – Los Angeles, Los Angeles,CA, United States
[6] Jonsson Comprehensive Cancer Center, University of California – Los Angeles, Los Angeles,CA, United States
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PLoS Computational Biology | 2019年 / 15卷 / 06期
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