Targeted Protein Destruction Advances in PROTACs and Other Degraders

被引:0
|
作者
Niewijk G.
机构
来源
关键词
D O I
10.1089/gen.40.12.13
中图分类号
学科分类号
摘要
[No abstract available]
引用
收藏
页码:42 / 44+46
相关论文
共 50 条
  • [31] Targeted protein knockdown using small molecule degraders
    Raina, Kanak
    Crews, Craig M.
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2017, 39 : 46 - 53
  • [32] Fundamental aspects of DMPK optimization of targeted protein degraders
    Cantrill, Carina
    Chaturvedi, Prasoon
    Rynn, Caroline
    Schaffland, Jeannine Petrig
    Walter, Isabelle
    Wittwer, Matthias B.
    DRUG DISCOVERY TODAY, 2020, 25 (06) : 969 - 982
  • [33] Macrocyclic peptides as a new class of targeted protein degraders
    Jing, Xuefei
    Mackay, Joel P.
    Passioura, Toby
    RSC CHEMICAL BIOLOGY, 2025, 6 (03): : 326 - 337
  • [34] Design and optimization strategies of PROTACs and its Application, Comparisons to other targeted protein degradation for multiple oncology therapies
    Malarvannan, M.
    Unnikrishnan, Sujith
    Monohar, S.
    Ravichandiran, V
    Paul, David
    BIOORGANIC CHEMISTRY, 2025, 154
  • [35] Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs
    Naito, Mikihiko
    Ohoka, Nobumichi
    Shibata, Norihito
    Tsukumo, Yoshinori
    FRONTIERS IN CHEMISTRY, 2019, 7
  • [36] Discovery of ganoderic acid A (GAA) PROTACs as MDM2 protein degraders for the treatment of breast cancer
    Li, Yan
    Li, Guangyu
    Zuo, Chenwei
    Wang, Xiaolin
    Han, Fang
    Jia, Yi
    Shang, Hai
    Tian, Yu
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 270
  • [37] RNA-PROTACs: Degraders of RNA-Binding Proteins
    Ghidini, Alice
    Clery, Antoine
    Halloy, Francois
    Allain, Frederic H. T.
    Hall, Jonathan
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (06) : 3163 - 3169
  • [38] Targeted protein degraders march towards the clinic for neurodegenerative diseases
    Hassan, Md. Imtaiyaz
    Kumar, Dhiraj
    AGEING RESEARCH REVIEWS, 2022, 78
  • [39] PROTAC™ targeted protein degraders: Exciting modality for drug discovery
    Araujo, Erika
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [40] Design and optimization of targeted protein degraders: Leveraging computational tools
    Che, Ye
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258