Research Progress on Contamination Levels, Analytical Methods and Processing Effects of Pyrrolizidine Alkaloids in Food

被引:0
|
作者
Liu H. [1 ]
Mu T. [1 ]
Lin L. [1 ]
Geng J. [1 ]
Jiang J. [1 ]
机构
[1] Beijing Institute of Food Inspection, Beijing Municipal Center for Food Safety Monitoring and Risk Assessment, Key Laboratory of Key Technologies of Major Comprehensive Guarantee of Food Safety for State Market Regulation, Beijing
关键词
analytical methods; food; food processing; natural toxins; pyrrolizidine alkaloids;
D O I
10.13386/j.issn1002-0306.2023020287
中图分类号
学科分类号
摘要
Pyrrolizidine alkaloids (PAs) are a class of natural toxins produced by plant secondary metabolism, of which unsaturated PAs and most pyrrolizidine alkaloid N-oxides (PANOs) have multiple toxic effects. These toxic components can be transmitted through food supplements or food chain to threaten human health. To date, PAs have been found to be widely present in a variety of food and agricultural products such as honey and tea, highlighting their occurrence as a concerning food safety issue. Therefore, this paper summarizes the contamination levels and possible contamination pathways of PAs in different matrices of different countries, and reviews the latest advances and development trends in pretreatment methods and analytical detection techniques or cooking preparation on the stability of PAs contaminants, aiming to provide warning and reference basis for the detection research, safety risk assessment and control of PAs in foods. © 2023 The Author(s).
引用
收藏
页码:392 / 403
页数:11
相关论文
共 99 条
  • [1] JIA N, ZENG S, CHEN W, Et al., Application of liquid chromatographymass spectrometry technology in the detection of pyrrolizidine alkaloids in agricultural products[J], Journal of Physics: Conference Series, 2021, 1, (2021)
  • [2] CASADO N, MORANTE-ZARCERO S, SIERRA I., Application of the QuEChERS strategy as a useful sample preparation tool for the multiresidue determination of pyrrolizidine alkaloids in food and feed samples:A critical overview[J], Applied Sciences, 12, 9, (2022)
  • [3] ZHU L, HUA R M, WANG L Y, Et al., Research progress on detection and analysis methods of pyrrolizidine alkaloids in plants[J], Quality and Safety of Agro-Products, 2021, 4
  • [4] JANK B, RATH J., The risk of pyrrolizidine alkaloids in human food and animal feed[J], Trends in Plant Science, 22, 3, (2017)
  • [5] TANG J, CHENG M., Recent progress in the research on pyrrolizidine alkaloids from Chinese medicinal herb “Zicao” and their metabolic toxicity[J], Acta Pharmaceutica Sinica, 54, 3, pp. 420-431, (2019)
  • [6] SCHRAMM S, KOHLER N, ROZHON W., Pyrrolizidine alkaloids: biosynthesis, biological activities and occurrence in crop plants [J], Molecules, 24, 3, (2019)
  • [7] MA C, LIU Y, ZHU L, Et al., Determination and regulation of hepatotoxic pyrrolizidine alkaloids in food:A critical review of recent research[J], Food and Chemical Toxicology, 119, (2018)
  • [8] HE Y, WU X, MA J, Et al., Hepatotoxicity evaluation on foodborne pyrrolizidine alkaloids, The FASEB Journal, 563, (2018)
  • [9] HAN H, JIANG C, WANG C, Et al., Development, optimization, validation and application of ultra high performance liquid chromatography tandem mass spectrometry for the analysis of pyrrolizidine alkaloids and pyrrolizidine alkaloid N-oxides in teas and weeds[J], Food Control, 132, (2022)
  • [10] CHEN L, MULDER P P J, LOUISSE J, Et al., Risk assessment for pyrrolizidine alkaloids detected in (herbal) teas and plant food supplements[J], Regulatory Toxicology and Pharmacology, 86, (2017)