Potential of quantum machine learning for solving the real-world problem of cancer classification

被引:0
|
作者
Ghobadi, Mohadeseh Zarei
Afsaneh, Elaheh
机构
[1] Independent Researcher, Tehran, Iran
关键词
Quantum machine learning; QML; Real-world problem; Classification; Cancer;
D O I
10.1007/s42452-024-06220-6
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Quantum machine learning (QML) algorithms have demonstrated the power of quantum computing for solving complex problems and big data in certain tasks. In this study, we explore the capabilities of QML for the classification of real-world biological large datasets including ten different cancer types based on gene expression values. By comparing the classification results obtained from the quantum algorithm with those from classical approaches, we disclose that the QML algorithm overall achieves comparable and reliable results. Moreover, we identify novel biomarkers that can contribute to the understanding of cancer biology. Some of these biomarkers are consistent with DNA promoter methylation. Our findings highlight the potential of QML in cancer classification and biomarker discovery, paving the way for future advancements in other disease research and clinical applications. QML could be implemented on real-world datasets to classify cancer types and identify biomarkers.QSVM outperformed some classical models in classification of ten cancer datasets.The novel biomarkers were found using quantum machine learning approach.Findings demonstrate the potential of QML in medical research and biomarker discovery.
引用
收藏
页数:12
相关论文
共 50 条
  • [31] THE STATUS OF REAL-WORLD ANALYSIS PROBLEM-SOLVING USING RIS
    THONNARD, N
    ARLINGHAUS, HF
    WILLIS, RD
    TAYLOR, EH
    WRIGHT, MC
    DAVIS, WA
    SPAAR, MT
    MOORE, LJ
    INSTITUTE OF PHYSICS CONFERENCE SERIES, 1991, (114): : 271 - 274
  • [32] Solving a Real-World Urban Postal Service System Redesign Problem
    Yu, Hao
    Sun, Xu
    Solvang, Wei Deng
    Laporte, Gilbert
    SCIENTIFIC PROGRAMMING, 2021, 2021
  • [33] CHILDRENS SPONTANEOUS USE OF REAL-WORLD INFORMATION IN PROBLEM-SOLVING
    MAJERES, RL
    FOX, R
    JOURNAL OF GENETIC PSYCHOLOGY, 1984, 144 (01): : 89 - 97
  • [34] Solving a Real-World Optimization Problem Using Proximal Policy Optimization with Curriculum Learning and Reward Engineering
    Pendyala, Abhijeet
    Atamna, Asma
    Glasmachers, Tobias
    MACHINE LEARNING AND KNOWLEDGE DISCOVERY IN DATABASES-APPLIED DATA SCIENCE TRACK, PT X, ECML PKDD 2024, 2024, 14950 : 150 - 165
  • [35] Solving a Higgs optimization problem with quantum annealing for machine learning
    Mott, Alex
    Job, Joshua
    Vlimant, Jean-Roch
    Lidar, Daniel
    Spiropulu, Maria
    NATURE, 2017, 550 (7676) : 375 - +
  • [36] Solving a Higgs optimization problem with quantum annealing for machine learning
    Alex Mott
    Joshua Job
    Jean-Roch Vlimant
    Daniel Lidar
    Maria Spiropulu
    Nature, 2017, 550 : 375 - 379
  • [37] Machine Learning and Real-World Data to Predict Lung Cancer Risk in Routine Care
    Chandran, Urmila
    Reps, Jenna
    Yang, Robert
    Vachani, Anil
    Maldonado, Fabien
    Kalsekar, Iftekhar
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2023, 32 (03) : 337 - 343
  • [38] Machine Learning Prediction of Early Recurrence in Gastric Cancer: A Nationwide Real-World Study
    Zhang, Xing-Qi
    Huang, Ze-Ning
    Wu, Ju
    Liu, Xiao-Dong
    Xie, Rong-Zhen
    Wu, Ying-Xin
    Zheng, Chang-Yue
    Zheng, Chao-Hui
    Li, Ping
    Xie, Jian-Wei
    Wang, Jia-Bin
    He, Qi-Chen
    Qiu, Wen-Wu
    Tang, Yi-Hui
    Zhang, Hao-Xiang
    Zhou, Yan-Bing
    Lin, Jian-Xian
    Huang, Chang-Ming
    ANNALS OF SURGICAL ONCOLOGY, 2025, 32 (04) : 2637 - 2650
  • [39] Simulation of colorectal cancer clinical trials using real-world data and machine learning
    Chen, Zhaoyi
    Zhang, Hansi
    George, Thomas
    Prosperi, Mattia
    Guo, Yi
    Braithwaite, Dejana
    Shenkman, Elizabeth
    Licht, Jonathan
    Bian, Jiang
    CLINICAL CANCER RESEARCH, 2021, 27 (05)
  • [40] A Fuzzy Grouping Genetic Algorithm for Solving a Real-World Virtual Machine Placement Problem in a Healthcare-Cloud
    Alharbe, Nawaf
    Aljohani, Abeer
    Rakrouki, Mohamed Ali
    ALGORITHMS, 2022, 15 (04)