A stable DNA duplex containing a non-hydrogen-bonding and non-shape-complementary base couple: Interstrand stacking as the stability determining factor

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作者：
机构：
[1] Brotschi, Christine
[2] Hberli, Adrian
[3] Leumann, Christian J.
来源：
Leumann, C.J. (leumann@ioc.unibe.ch) | 2001年 / Wiley-VCH Verlag卷 / 40期
关键词：
Hydrogen bonds - Organic compounds;
D O I：
10.1002/1521-3773(20010817)40:163.0.CO;2-Y
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摘要：
The stabilizing effect of a dG:dC base-pair can also be imparted to a DNA duplex by a non-hydrogen- bonding, non-shape-complementary nucleoside analogue when interstrand stacking interactions come into play. This is the case, for example, with dBP, which has a bipyridyl (BP) residue as a nucleobase surrogate (the picture shows a dBP:dBP pair).
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