Synthesis and Application of Quinolinone-coumarin-based Colorimetric Fluorescent Probe for Recognition of Hg2+

A novel quinolinone-coumarin probe, 7-diethylamino-3-[3-(7-diethylamino) coumarinyl-3-oxopropenyl] quinolin-2-one(QCO), was designed and synthesized for the detection of Hg2+ in an aqueous solution. QCO exhibited high selectivity and strong anti-interference for Hg2+. In addition, Hg2+ caused significant color changes of QCO solution, which could be identified with the naked eye. In the colorimetric method, the absorbance ratio A500/A380 had a good linear relationship with the Hg2+ concentration, and its detection limit was 2.62×10-8 mol/L. In the fluorescence method, the detection limit of probe QCO for Hg2+ was 5.42×10-8 mol/L. The stoichiometry of 1:1(molar ratio) between QCO and Hg2+ was verified by Job's plot, MS and IR methods. Most remarkably, QCO could be used to detect Hg2+ in practical application by silicone board experiments and the standard recovery tests. © 2022, Editorial Department of Chem. J. Chinese Universities. All right reserved.