Chloro-hydroxyl-merocyanine based turn-on fluorescent probes for the detection of hydrazine in water and living cells

被引：0
|
作者：
Li, Kai-Bin [1 ,2 ]
Chen, Yiyu [3 ]
Zhou, Tianshuo [3 ]
Wang, Tianlin [3 ]
Wu, Dian [3 ]
Pan, Yuanjiang [1 ]
Zhang, Siqi [2 ]
Shi, Wei [2 ]
Wang, Feiyi [3 ]
Ren, Jun [3 ]
机构：
[1] Department of Chemistry, Zhejiang University, Hangzhou,310027, China
[2] Department of Chemistry, Taizhou University, Jiaojiang,318000, China
[3] Collaborative Innovation Center for Advanced Organic Chemical Materials Co-constructed By the Province and Ministry & Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & State Key Laboratory of Biocataly
来源：
Dyes and Pigments | 2022年 / 200卷
基金：
中国国家自然科学基金;
关键词：
Chemical reagents - Fluorescent probes - Image-analysis - Living cell - Merocyanine - Merocyanine dye - Near-infrared emissions - Pesticide production - Simple reaction - Synthesised;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Hydrazine (N2H4) is a very important chemical reagent which has been widely used in the fields of chemistry industry, aerospace, pesticide production and others. However, N2H4 is highly toxic and prone to induce a variety of diseases. Hence, we designed two fluorescent probes (CH–NO1, CH–NO2) based on chloro-hydroxyl-merocyanine (CHMC) with similar recognition groups. The two probes were synthesized by a simple reaction coupling between CHMC dye and two alkyl bromine compounds. Both probes showed specific off-on response to N2H4 in aqueous solution with nanomolar LOD (28 nM for CH–NO1 and 38 nM for CH–NO2), and without interference by a range of amino acids, anions and cations. Moreover, CH–NO1 can be used for both environmental and biological monitoring of N2H4. © 2022 Elsevier Ltd
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