Chloro-hydroxyl-merocyanine based turn-on fluorescent probes for the detection of hydrazine in water and living cells

被引：0

作者：

Li, Kai-Bin ^{[1
,2
]}

Chen, Yiyu ^{[3
]}

Zhou, Tianshuo ^{[3
]}

Wang, Tianlin ^{[3
]}

Wu, Dian ^{[3
]}

Pan, Yuanjiang ^{[1
]}

Zhang, Siqi ^{[2
]}

Shi, Wei ^{[2
]}

Wang, Feiyi ^{[3
]}

Ren, Jun ^{[3
]}

机构：

[1] Department of Chemistry, Zhejiang University, Hangzhou,310027, China

[2] Department of Chemistry, Taizhou University, Jiaojiang,318000, China

[3] Collaborative Innovation Center for Advanced Organic Chemical Materials Co-constructed By the Province and Ministry & Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & State Key Laboratory of Biocataly

来源：

Dyes and Pigments | 2022年 / 200卷

基金：

中国国家自然科学基金;

关键词：

Chemical reagents - Fluorescent probes - Image-analysis - Living cell - Merocyanine - Merocyanine dye - Near-infrared emissions - Pesticide production - Simple reaction - Synthesised;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Hydrazine (N2H4) is a very important chemical reagent which has been widely used in the fields of chemistry industry, aerospace, pesticide production and others. However, N2H4 is highly toxic and prone to induce a variety of diseases. Hence, we designed two fluorescent probes (CH–NO1, CH–NO2) based on chloro-hydroxyl-merocyanine (CHMC) with similar recognition groups. The two probes were synthesized by a simple reaction coupling between CHMC dye and two alkyl bromine compounds. Both probes showed specific off-on response to N2H4 in aqueous solution with nanomolar LOD (28 nM for CH–NO1 and 38 nM for CH–NO2), and without interference by a range of amino acids, anions and cations. Moreover, CH–NO1 can be used for both environmental and biological monitoring of N2H4. © 2022 Elsevier Ltd

引用

共 50 条

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