Post-Surgical Non-Invasive Wound Healing Monitoring in Oropharyngeal Mucosa

Postoperative bleeding is the most significant complication of tonsillectomy. Regular monitoring of post-surgical wound healing in the pharynx is required. For this purpose, we propose endoscope-based non-invasive perfusion mapping and quantification. The combination of imaging photoplethysmography and image processing provides automated wound area selection and microcirculation characterization. In this feasibility study, we demonstrate the first results of the proposed approach to wound monitoring in clinical trial on eight patients after tonsillectomy. Combination of probe-based optical system and image processing algorithms can provide the valuable and consistent data on perfusion distribution. The quantitative microcirculation data obtained 1, 4, and 7 days after surgery are in good agreement with existing monitoring protocols. Quantitative perfusion mapping of mucosa may provide valuable data on tissue healing process after surgical interventions. The endoscope-based setup for non-invasive perfusion monitoring is proposed. The combination of imaging photoplethysmography and an image processing algorithm provides automated frame-by-frame wound area selection and perfusion calculation. The first results of the proposed approach to monitoring wound healing after tonsillectomy are presented.image