Serial 18F-FDG PET/CT Revealing Mixed Histiocytosis in a Pediatric Patient

被引：0

作者：

Singh, Karan ^{[1
]}

Lau, Loretta ^{[2
,3
,4
]}

Wegner, Eva A. ^{[5
,6
]}

Rossleigh, Monica A. ^{[5
,6
]}

Shon, Ivan Ho ^{[1
,7
]}

机构：

[1] Prince Wales & Sydney Childrens Hosp, Dept Nucl Med & PET, Randwick, Australia

[2] UNSW Sydney, Childrens Canc Inst, Lowy Canc Ctr, Kensington, Australia

[3] UNSW Sydney, Sch Clin Med, UNSW Med & Hlth, Kensington, NSW, Australia

[4] Sydney Childrens Hosp, Kids Canc Ctr, Randwick, NSW, Australia

[5] Prince Wales Hosp, Dept Nucl Med & PET, Randwick, Australia

[6] Univ NSW, Fac Med, Sydney, NSW, Australia

[7] UNSW Med & Hlth, Sch Clin Med, Randwick Clin Campus, Kensington, NSW, Australia

来源：

CLINICAL NUCLEAR MEDICINE | 2024年 / 49卷 / 10期

关键词：

histiocytosis; mixed; pediatrics; FDG PET/CT; LANGERHANS CELL HISTIOCYTOSIS;

D O I：

10.1097/RLU.0000000000005422

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 6-month-old boy presented with a left parietal soft tissue swelling and CT findings of multiple calvarial lytic lesions. F-18-FDG PET/CT demonstrated hypermetabolic lesions in the left parietal, right occipital, and right femoral bones. The left parietal lesion was excised, and pathology was consistent with Langerhans cell histiocytosis. Interim PET assessment following induction chemotherapy demonstrated a "mixed metabolic response" with discordant rise in metabolic activity of the right femoral lesion. Subsequent core biopsy of the femoral lesion revealed a non-Langerhans cell histiocytosis, likely juvenile xanthogranuloma. Here we describe a rare pediatric case of mixed histiocytosis, unveiled by serial F-18-FDG PET/CT.

引用

页码：e518 / e520

页数：3

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