Assessment of central vein sign and paramagnetic rim lesions in pediatric multiple sclerosis

被引：0
|
作者：
Margoni, Margoni [1 ,2 ,3 ]
Preziosa, Paolo [1 ,2 ,4 ]
Pagani, Elisabetta [1 ]
Storelli, Loredana [1 ]
Gueye, Mor [1 ,2 ,4 ]
Moiola, Lucia [2 ]
Filippi, Massimo [1 ,2 ,3 ,4 ,5 ]
Rocca, Maria A. [1 ,2 ,4 ]
机构：
[1] IRCCS San Raffaele Sci Inst, Div Neurosci, Neuroimaging Res Unit, Milan, Italy
[2] IRCCS San Raffaele Sci Inst, Neurol Unit, Milan, Italy
[3] IRCCS San Raffaele Sci Inst, Neurorehabil Unit, Milan, Italy
[4] Univ Vita Salute San Raffaele, Milan, Italy
[5] IRCCS San Raffaele Sci Inst, Neurophysiol Serv, Milan, Italy
来源：
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY | 2024年 / 11卷 / 11期
关键词：
BRAIN-LESIONS;
D O I：
10.1002/acn3.52208
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The evaluation of white matter lesions (WMLs) showing the central vein sign (CVS) and paramagnetic rim lesions (PRLs) has been suggested to enhance the diagnostic work-up of adult multiple sclerosis (MS). We aimed to evaluate the fulfillment of different CVS criteria and the added value of PRLs in 22 pediatric MS patients. Eleven patients (50%) fulfilled the 40%-rule threshold. Nineteen (86%) patients had >= 3 CVS+ WMLs or >= 1 PRL, whereas 17 (77%) had >= 6 CVS+ WMLs or >= 1 PRL. A simplified CVS-based approach, with the combined evaluation of >= 1 PRL in patients with >= 6 CVS+ WMLs, may improve MS diagnosis in pediatric patients.
引用
收藏
页码：3031 / 3036
页数：6
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