Effect of coffee intake on appetite parameters in woman with overweight or obesity: A pilot crossover randomized trial

Introduction: Coffee consumption has demonstrated an effect on the regulation of appetite, causing less hunger and/or greater satiety; however, its effects are not well known in woman with overweight or obesity. Therefore, this study aimed to evaluate the effect of coffee consumption on hunger, satiety, sensory specific desire (SSD), and dietary intake in women with overweight or obesity. Methodology: A randomized crossover clinical trial was realized in 3 sessions: in the first session a clinical history, anthropometric measurements and body composition analysis were performed; in sessions 2 and 3 the participants randomly consumed 240 mL of coffee with 6 mg/caffeine/kg of weight or 240 mL of water along with a standardized breakfast. At fasting and every 30 min after breakfast for the next 3 h, appetite sensations and SSD were recorded using visual analog scales. Blood samples were taken at fasting, 30 and 180 min after breakfast. Dietary intake was recorded in the rest of the intervention days. Results: In the coffee intervention there was an increased desire for sweet foods, higher fructose intake during the rest of the day, and higher triglyceride levels than with the water intervention. No differences were detected in ghrelin or cholecystokinin. Conclusions: Coffee consumption may lead to higher triglycerides and higher intake of simple sugars, mainly fructose, through changes in the SSD. Clinical Trial Registration: https://clinicaltrials.gov/ NCT05774119. (c) 2024 SEEN y SED. Published by Elsevier Espana, a, S.L.U. All rights reserved.