The Activation of FGFR1/FRS2 Pathway and the Interaction with EGFR Pathway in Low-Grade Osteosarcoma

被引:0
|
作者
Peng, Ran [1 ]
Xie, You [1 ]
Jing, Wenyi [1 ]
Qiu, Yan [1 ]
He, Xin [1 ]
Lu, Yang [1 ]
Zhang, Hongying [1 ]
机构
[1] Sichuan Univ, West China Hosp, Chengdu, Peoples R China
关键词
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
63
引用
收藏
页码:S70 / S71
页数:2
相关论文
共 50 条
  • [21] Association of the FGFR1 mutation with spontaneous hemorrhage in low-grade gliomas in pediatric and young adult patients
    Ishi, Yukitomo
    Yamaguchi, Shigeru
    Hatanaka, Kanako C.
    Okamoto, Michinari
    Motegi, Hiroaki
    Kobayashi, Hiroyuki
    Terasaka, Shunsuke
    Houkin, Kiyohiro
    JOURNAL OF NEUROSURGERY, 2021, 134 (03) : 733 - 741
  • [22] Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the MAPK Pathway
    Lu, Yuhong
    Liu, Yanfeng
    Oeck, Sebastian
    Zhang, Gary J.
    Schramm, Alexander
    Glazer, Peter M.
    CANCER RESEARCH, 2020, 80 (21) : 4655 - 4667
  • [23] FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/TGF-β/β-catenin pathway
    Shuang-Qing Li
    Chao Tu
    Lu Wan
    Rui-Qi Chen
    Zhi-Xi Duan
    Xiao-Lei Ren
    Zhi-Hong Li
    Cell Division, 14
  • [24] The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells
    Cross, MJ
    Lu, LG
    Magnusson, P
    Nyqvist, D
    Holmqvist, K
    Welsh, M
    Claesson-Welsh, L
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 (08) : 2881 - 2893
  • [25] FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/ TGF-β/β-catenin pathway
    Li, Shuang-Qing
    Tu, Chao
    Wan, Lu
    Chen, Rui-Qi
    Duan, Zhi-Xi
    Ren, Xiao-Lei
    Li, Zhi-Hong
    CELL DIVISION, 2019, 14 (01)
  • [26] THE INFLUENCE OF DIFFERENT FGFR1 ALTERATIONS ON PEDIATRIC LOW-GRADE GLIOMA TUMOR BIOLOGY AND TARGETED THERAPY RESPONSE
    Morin, Eric
    DiGiacomo, Jeromy
    Novikov, Dana
    Malinowski, Seth
    Chow, Kin-Hoe
    Jones, David
    Alexandrescu, Sanda
    Ligon, Keith
    Bandopadhayay, Pratiti
    NEURO-ONCOLOGY, 2022, 24 : 99 - 99
  • [27] BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas
    Pfister, Stefan
    Janzarik, Wibke G.
    Remke, Marc
    Ernst, Aurelie
    Werft, Wiebke
    Becker, Natalia
    Toedt, Grischa
    Wittmann, Andrea
    Kratz, Christian
    Olbrich, Heike
    Ahmadi, Rezvan
    Thieme, Barbara
    Joos, Stefan
    Radiwimmer, Bernhard
    Kulozik, Andreas
    Pietsch, Torsten
    Herold-Mende, Christel
    Gnekow, Astrid
    Reifenberger, Guido
    Korshunov, Andrey
    Scheurlen, Wolfram
    Omran, Heymut
    Lichter, Peter
    JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (05): : 1739 - 1749
  • [28] Novel RAF Fusions in Pediatric Low-Grade Gliomas Demonstrate MAPK Pathway Activation
    Lind, Katherine T.
    Chatwin, Hannah, V
    DeSisto, John
    Coleman, Philip
    Sanford, Bridget
    Donson, Andrew M.
    Davies, Kurtis D.
    Willard, Nicholas
    Ewing, Calvin A.
    Knox, Aaron J.
    Levy, Jean M. Mulcahy
    Gilani, Ahmed
    Green, Adam L.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021, 80 (12): : 1099 - 1107
  • [29] Activation of FGFR1β signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells
    M A Karajannis
    L Vincent
    R DiRenzo
    S V Shmelkov
    F Zhang
    E J Feldman
    P Bohlen
    Z Zhu
    H Sun
    P Kussie
    S Rafii
    Leukemia, 2006, 20 : 979 - 986
  • [30] Activation of FGFR1β signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells
    Karajannis, M. A.
    Vincent, L.
    DiRenzo, R.
    Shmelkov, S. V.
    Zhang, F.
    Feldman, E. J.
    Bohlen, P.
    Zhu, Z.
    Sun, H.
    Kussie, P.
    Rafii, S.
    LEUKEMIA, 2006, 20 (06) : 979 - 986