Germline regulation of the somatic mitochondrial stress response

被引：1
|
作者：
Zhou, Liankui [1 ,2 ]
Liu, Ying [1 ,2 ,3 ]
机构：
[1] Peking Univ, Inst Mol Med, Coll Future Technol, State Key Lab Membrane Biol,New Cornerstone Sci La, Beijing 100871, Peoples R China
[2] Peking Univ, Acad Adv Interdisciplinary Studies, Ctr Life Sci, Beijing, Peoples R China
[3] Peking Univ, Beijing Adv Innovat Ctr Genom, Beijing, Peoples R China
来源：
TRENDS IN CELL BIOLOGY | 2024年 / 34卷 / 08期
关键词：
UPR;
D O I：
10.1016/j.tcb.2024.07.004
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Mitochondria are pivotal organelles for cellular energy production and the regulation of stress responses. Recent research has elucidated complex mechanisms through which mitochondrial stress in one tissue can impact distant tissues, thereby promoting overall organismal health. Two recent studies by Shen et al. and Charmpilas et al. have demonstrated that an intact germline serves as a crucial signaling hub for the activation of the somatic mitochondrial unfolded protein response (UPRmt) in Caenorhabditis elegans. .
引用
收藏
页码：617 / 619
页数：3
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