Primary mucinous adenocarcinoma of the anterior mediastinum with HER-2 mutation: A rare case report

被引：0
|
作者：
Zhang, Yu [1 ]
Rui, Jinqiu [1 ,2 ]
Liang, Jun
Lin, Li [1 ]
机构：
[1] Peking Univ, Int Hosp, Dept Oncol Ctr, Life Pk Rd,Zhong Guancun Life Sci Pk, Beijing 102206, Peoples R China
[2] Geneplus Beijing, Dept Med, Beijing 102206, Peoples R China
来源：
HELIYON | 2024年 / 10卷 / 14期
关键词：
Case report; Mucinous adenocarcinoma; Chemoradiotherapy; Anterior mediastinum; HER2; THYMUS;
D O I：
10.1016/j.heliyon.2024.e34346
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We report the case of a 68-year-old male whose Computed Tomography (CT) scan presented a mass (68*62*54 mm) of the right anterior mediastinal and pathologically diagnosis was mucinous adenocarcinoma(MA). The peripheral vessels are surrounded by the big mass in the anterior mediastinum which was associated with multiple metastases, thus we performed palliative chemoradiotherapy and we tried Human Epidermal Growth Factor Receptor-2 (HER-2) inhibitors based on the Next Generation Sequencing. The patient passed away 16 months after the onset of the disease. In this report, we review the rare case of anterior mediastinum MA as well as perspectives for potential future treatments.
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页数：5
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