Broad-spectrum antibiotic prescriptions are discontinued unevenly throughout the week

被引：7

作者：

Kokado, R. ^{[1
,2
]}

Hagiya, H. ^{[1
]}

Morii, D. ^{[1
]}

Okuno, H. ^{[1
]}

Yamamoto, N. ^{[1
]}

Hamaguchi, S. ^{[1
]}

Yoshida, H. ^{[1
]}

Miwa, Y. ^{[2
]}

Tamano, K. ^{[1
]}

机构：

[1] Osaka Univ Hosp, Div Infect Control & Prevent, 2-15 Yamadaoka, Suita, Osaka 5650871, Japan

[2] Osaka Univ Hosp, Dept Pharm, Osaka, Japan

来源：

JOURNAL OF HOSPITAL INFECTION | 2019年 / 101卷 / 04期

关键词：

Antibiotics; Antimicrobial resistance; Antimicrobial stewardship; ADMISSION; CARE;

D O I：

10.1016/j.jhin.2018.11.004

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In order to investigate prescribing patterns of in-hospital broad-spectrum antibiotics (antimeticillin-resistant Staphylococcus aureus drugs, carbapenems and piperacillin/tazobactam), data on the distribution of antibiotic initiation and discontinuation throughout the week were analysed at Osaka University Hospital, Japan. No significant differences in the number of initiations were found between weekdays. However, broad-spectrum antibiotics were disproportionately discontinued on Tuesdays or on the second day after a holiday. This study suggests that broad-spectrum antibiotics tend to be continued over weekends or holidays and discontinued thereafter; this is likely to be due to behavioural factors beyond medical indications, and needs to be addressed in future antimicrobial stewardship initiatives. (C) 2018 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：471 / 474

页数：4

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