Molybdenum-Promoted Synthesis of Benzo[4,5]imidazo[1,2-c]quinazolin-6(5H)-ones via Nitro Reduction and Ring Expansion

被引：0

作者：

Zhao, Ran ^{[1
]}

Meng, Zerui ^{[1
]}

Meng, Xiaoru ^{[1
]}

Huang, Xinrui ^{[1
]}

Meng, Xiangwei ^{[2
]}

Xie, Caixia ^{[1
]}

机构：

[1] Shandong Univ Technol, Sch Chem & Chem Engn, 266 West Xincun Rd, Zibo 255049, Peoples R China

[2] Binzhou Med Univ, Zibo Cent Hosp, Dept Drug Clin Trials, 54 Gongqingtuan Xi Rd, Zibo 255036, Peoples R China

来源：

CHEMISTRYSELECT | 2024年 / 9卷 / 34期

关键词：

Benzo[4,5]imidazo[1,2-c]quinazolin-6(5H)-one; Cyclization; Isatins; Nitroreduction; Mo(CO)(6); MEDIATED ANNULATION; METHODOLOGY;

D O I：

10.1002/slct.202403399

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and efficient method to construct benzo[4,5]imidazo[1,2-c]quinazolin-6(5H)-one skeleton was reported. A powerful functional group transformation strategy of -NO2 transformed into -NH2 was involved in this method. Only Mo(CO)(6) was used in the reaction, which acted as both reductant and cyclization accelerator. And a series of benzo[4,5]imidazo[1,2-c]quinazolin-6(5H)-one derivatives were obtained.

引用

页数：5

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