Light-based 3D bioprinting technology applied to repair and regeneration of different tissues: A rational proposal for biomedical applications

被引:6
|
作者
Fang, Wenzhuo [1 ]
Yu, Zhenwei [1 ]
Gao, Guo [2 ]
Yang, Ming [1 ]
Du, Xuan [2 ]
Wang, Ying [1 ]
Fu, Qiang [1 ]
机构
[1] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 6, Shanghai Eastern Inst Urol Reconstruct, Sch Med,Dept Urol, Shanghai 200233, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Elect Informat & Elect Engn, Sch Sensing Sci & Engn, Key Lab Thin Film & Micro Fabricat,Minist Educ, Shanghai 200240, Peoples R China
基金
中国国家自然科学基金; 上海市自然科学基金;
关键词
Light-based 3D bioprinting 1; Bio-ink; 2; Tissue engineering 3; Photo-crosslinked polymers 4; Hydrogel; 5; DECELLULARIZED EXTRACELLULAR-MATRIX; CROSS-LINKABLE HYDROGELS; MECHANICAL-PROPERTIES; HYALURONIC-ACID; IN-VITRO; METHACRYLATED GELATIN; PRINTED SCAFFOLDS; BONE; FABRICATION; CONSTRUCTS;
D O I
10.1016/j.mtbio.2024.101135
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
3D bioprinting technology, a subset of 3D printing technology, is currently witnessing widespread utilization in tissue repair and regeneration endeavors. In particular, light-based 3D bioprinting technology has garnered significant interest and favor. Central to its successful implementation lies the judicious selection of photosensitive polymers. Moreover, by fine-tuning parameters such as light irradiation time, choice of photoinitiators and crosslinkers, and their concentrations, the properties of the scaffolds can be tailored to suit the specific requirements of the targeted tissue repair sites. In this comprehensive review, we provide an overview of commonly utilized bio-inks suitable for light-based 3D bioprinting, delving into the distinctive characteristics of each material. Furthermore, we delineate strategies for bio-ink selection tailored to diverse repair locations, alongside methods for optimizing printing parameters. Ultimately, we present a coherent synthesis aimed at enhancing the practical application of light-based 3D bioprinting technology in tissue engineering, while also addressing current challenges and future prospects.
引用
收藏
页数:18
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