Radiation-Induced Angiosarcoma Arising in Bilateral Breast: A Case Report

被引：0

作者：

Tsuji, Wakako ^{[1
]}

Yoshikawa, Katsuhiro ^{[2
]}

Fujisawa, Fumie ^{[3
]}

Yamauchi, Chikako ^{[4
]}

Sugimoto, Akihiko ^{[5
]}

机构：

[1] Shiga Gen Hosp, Dept Breast Surg, Moriyama, Japan

[2] Shiga Gen Hosp, Dept Plast Surg, Moriyama, Japan

[3] Shiga Gen Hosp, Dept Oncol, Moriyama, Japan

[4] Shiga Gen Hosp, Dept Radiat Oncol, Moriyama, Japan

[5] Shiga Gen Hosp, Dept Diagnost Pathol, Moriyama, Japan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 09期

关键词：

recurrence; taxane; wide skin grafting; surgical resection with an adequate margin; breast-conserving therapy; bilateral radiation-induced angiosarcoma;

D O I：

10.7759/cureus.68782

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Radiation-induced angiosarcoma is a highly aggressive malignancy. We encountered a case of angiosarcoma arising in the bilateral breast seven years after partial mastectomy and the last radiation therapy. As recommended, wide resection with skin grafting was performed to ensure negative surgical margins. After surgery, taxane-based chemotherapy was administered. However, adjuvant chemotherapy was discontinued because of drug-induced institutional pneumonia. Eighteen months postoperatively, angiosarcoma recurred in subcutaneous, lymph nodes, lungs, and bones. The disease progressed too rapidly, and the patient died two months after recurrence.

引用

页数：7

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