Bone Morphogenetic Proteins: A Promising Approach for Enhancing Fracture Healing

被引：0
|
作者：
Nair, Vinod [1 ]
Patil, Vishal S. [1 ]
Todkar, Amogh [1 ]
Shah, Meet [1 ]
Devarmani, Shivappa [1 ]
机构：
[1] Dr D Y Patil Vidyapeeth, Dr D Y Patil Med Coll Hosp & Res Ctr, Orthoped, Pune, India
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2024年 / 16卷 / 08期
关键词：
non-union; osteosynthesis; fracture healing; bone morphogenetic proteins; bone;
D O I：
10.7759/cureus.66619
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Fracture healing is a complex biological process that can be delayed or impaired in certain situations. Bone morphogenetic proteins (BMPs) have emerged as a promising therapeutic strategy to promote bone formation and accelerate fracture healing. This editorial talks about the current understanding of BMPs, their mechanisms of action in fracture healing, and their potential applications in orthopedic trauma management. We also discuss the ongoing challenges and future directions for research on BMPs in fracture healing.
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Bone morphogenetic proteins in the development and healing of synovial joints
    Edwards, CJ
    Francis-West, PH
    SEMINARS IN ARTHRITIS AND RHEUMATISM, 2001, 31 (01) : 33 - 42
  • [22] Clinical application of bone morphogenetic proteins for bone healing: a systematic review
    Gopal Shankar Krishnakumar
    Alice Roffi
    Davide Reale
    Elizaveta Kon
    Giuseppe Filardo
    International Orthopaedics, 2017, 41 : 1073 - 1083
  • [23] Clinical application of bone morphogenetic proteins for bone healing: a systematic review
    Krishnakumar, Gopal Shankar
    Roffi, Alice
    Reale, Davide
    Kon, Elizaveta
    Filardo, Giuseppe
    INTERNATIONAL ORTHOPAEDICS, 2017, 41 (06) : 1073 - 1083
  • [24] Circulating bone morphogenetic protein levels and delayed fracture healing
    van Baardewijk, Laurens J.
    van der Ende, Jacob
    Lissenberg-Thunnissen, Suzanne
    Romijn, Loes M.
    Hawinkels, Lukas J. A. C.
    Sier, Cornelis F. M.
    Schipper, Inger B.
    INTERNATIONAL ORTHOPAEDICS, 2013, 37 (03) : 523 - 527
  • [25] Circulating bone morphogenetic protein levels and delayed fracture healing
    Laurens J. van Baardewijk
    Jacob van der Ende
    Suzanne Lissenberg-Thunnissen
    Loes M. Romijn
    Lukas J. A. C. Hawinkels
    Cornelis F. M. Sier
    Inger B. Schipper
    International Orthopaedics, 2013, 37 : 523 - 527
  • [26] Bone morphogenetic proteins and Smad expression in ovine tendon-bone healing
    Yu, Yan
    Bliss, James P.
    Bruce, Warrick J. A.
    Walsh, William R.
    ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 2007, 23 (02): : 205 - 210
  • [27] Could the use of bone morphogenetic proteins in fracture healing do more harm than good to our patients?
    Delimar, Domagoj
    Smoljanovic, Tomislav
    Bojanic, Ivan
    INTERNATIONAL ORTHOPAEDICS, 2012, 36 (03) : 683 - 683
  • [28] Could the use of bone morphogenetic proteins in fracture healing do more harm than good to our patients?
    Domagoj Delimar
    Tomislav Smoljanovic
    Ivan Bojanic
    International Orthopaedics, 2012, 36 : 683 - 683
  • [29] Cochrane corner: bone morphogenetic protein (BMP) for fracture healing in adults
    Glass, G. E.
    Jain, A.
    JOURNAL OF HAND SURGERY-EUROPEAN VOLUME, 2013, 38E (04) : 447 - 449
  • [30] BONE MORPHOGENETIC PROTEINS (BMPS) - THERAPEUTIC POTENTIAL IN HEALING BONY DEFECTS
    WANG, EA
    TRENDS IN BIOTECHNOLOGY, 1993, 11 (09) : 379 - 383
12345