IL-21, B cells and CD4-CD8-T cells are key for resistance to Babesia microti infection in immunosuppressed hosts

被引:1
|
作者
Wilson, C. [1 ]
Su, J. -S. [1 ]
Silver, Z. [1 ]
Laurie, S. [2 ]
Telford, S.
Krause, P. J. [3 ]
Wortis, H. H. [2 ]
Vannier, E. [1 ]
机构
[1] Tufts Med Ctr, Boston, MA USA
[2] Tufts Univ, Sch Med, Boston, MA 02111 USA
[3] Yale Sch Med, New Haven, CT USA
关键词
D O I
10.1016/j.cyto.2012.06.090
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:521 / 521
页数:1
相关论文
共 50 条
  • [41] IL-6 promotes the differentiation of a subset of naive CD8+ T cells into IL-21-producing B helper CD8+ T cells
    Yang, Rui
    Masters, April R.
    Fortner, Karen A.
    Champagne, Devin P.
    Yanguas-Casas, Natalia
    Silberger, Daniel J.
    Weaver, Casey T.
    Haynes, Laura
    Rincon, Mercedes
    JOURNAL OF EXPERIMENTAL MEDICINE, 2016, 213 (11): : 2281 - 2291
  • [42] CD4-CD8-T cells contribute to the persistence of MHV-3 induced chronic viral hepatitis
    Zhang, Jiangguo
    Wang, Hongwu
    Yan, Weiming
    Wang, Xiaojing
    Xi, Dong
    Luo, Xiaoping
    Ning, Qin
    HEPATOLOGY, 2007, 46 (04) : 894A - 894A
  • [43] IL-21 Promotes CD4 T Cell Responses by Phosphatidylinositol 3-Kinase-Dependent Upregulation of CD86 on B Cells
    Attridge, Kesley
    Kenefeck, Rupert
    Wardzinski, Lukasz
    Qureshi, Omar S.
    Wang, Chun Jing
    Manzotti, Claire
    Okkenhaug, Klaus
    Walker, Lucy S. K.
    JOURNAL OF IMMUNOLOGY, 2014, 192 (05): : 2195 - 2201
  • [44] IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection
    Stanley Adoro
    Juan R. Cubillos-Ruiz
    Xi Chen
    Maud Deruaz
    Vladimir D. Vrbanac
    Minkyung Song
    Suna Park
    Thomas T. Murooka
    Timothy E. Dudek
    Andrew D. Luster
    Andrew M. Tager
    Hendrik Streeck
    Brittany Bowman
    Bruce D. Walker
    Douglas S. Kwon
    Vanja Lazarevic
    Laurie H. Glimcher
    Nature Communications, 6
  • [45] IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection
    Adoro, Stanley
    Cubillos-Ruiz, Juan R.
    Chen, Xi
    Deruaz, Maud
    Vrbanac, Vladimir D.
    Song, Minkyung
    Park, Suna
    Murooka, Thomas T.
    Dudek, Timothy E.
    Luster, Andrew D.
    Tager, Andrew M.
    Streeck, Hendrik
    Bowman, Brittany
    Walker, Bruce D.
    Kwon, Douglas S.
    Lazarevic, Vanja
    Glimcher, Laurie H.
    NATURE COMMUNICATIONS, 2015, 6
  • [46] IL-21 is increased in CD4+T cells and serum from patients with systemic lupus erythematosus
    Vinh Nguyen
    Siaton, Bernadette
    Rus, Violeta
    JOURNAL OF IMMUNOLOGY, 2009, 182
  • [47] TGF-β and IL-21 cooperatively stimulate activated CD8+ T cells to differentiate into Tc17 cells
    Chen, Hsin-Wei
    Tsai, Jy-Ping
    Yao, Tsung-You
    Hsieh, Chia -Ling
    Chen, I-Hua
    Liu, Shin-Jen
    IMMUNOLOGY LETTERS, 2016, 174 : 23 - 27
  • [48] CD4-CD8-T cells contribute to the persistence of viral hepatitis by striking a delicate balance in immune modulation
    Wang, Xiaojing
    Yan, Weiming
    Lu, Yulei
    Chen, Tao
    Sun, Ying
    Qin, Xiaomin
    Zhang, Jiangguo
    Han, Meifang
    Guo, Wei
    Wang, Hongwu
    Wu, Di
    Xi, Dong
    Luo, Xiaoping
    Ning, Qin
    CELLULAR IMMUNOLOGY, 2012, 280 (01) : 76 - 84
  • [49] Modulation of cytolytic activity of CD8+T cells by HIV-1-specific IL21+CD4+T cells
    Chevalier, M.
    Julg, B.
    Pyo, A.
    Flanders, M.
    Ranasinghe, S.
    Mueller, M.
    Kwon, D.
    Rychert, J.
    Lian, J.
    Altfeld, M.
    Walker, B.
    Streeck, H.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2010, 26 (10) : A6 - A6
  • [50] CD4+ T cells require either B cells or CD8+ T cells to control spread and pathogenesis of a neurotropic infection
    Solomos, Andreas C.
    O'Regan, Kevin J.
    Rall, Glenn F.
    VIROLOGY, 2016, 499 : 196 - 202