Overcoming efficiency limitations of CAR-T cell therapy in antigen-heterogeneous solid tumors

被引：0
|
作者：
Klampatsa, Astero [1 ]
机构：
[1] Inst Canc Res, Div Canc Therapeut, Thorac Oncol Immunotherapy Grp, 15 Cotswold Rd, London SM2 5NG, England
来源：
EXPERT OPINION ON BIOLOGICAL THERAPY | 2024年 / 24卷 / 09期
关键词：
CAR-T cell therapy; tumor antigen heterogeneity; antigen density; solid cancer; endogenous immune response; CAR-T bystander effects; epitope spreading;
D O I：
10.1080/14712598.2024.2399141
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：879 / 881
页数：3
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