Visible-Light-Induced Metal- and Photosensitizer-Free C(sp3)-H Phosphorylation of 3,4-Dihydroquinoxalin-2(1H)-ones with Diphenylphosphine Oxide

被引：2
|
作者：
Jia, Li [1 ]
Lu, Yanan [1 ]
Chen, Ying [1 ]
Zhong, Yu [1 ]
Zhao, Fen [1 ,2 ]
Zhou, Yongyun [1 ,2 ]
机构：
[1] Yunnan Minzu Univ, Yunnan Key Lab Chiral Funct Subst Res & Applicat, Kunming 650500, Yunnan, Peoples R China
[2] Yunnan Minzu Univ, Dept Sch Chem & Environm, Kunming 650500, Yunnan, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 16期
基金：
中国国家自然科学基金;
关键词：
Photosensitizers;
D O I：
10.1021/acs.joc.4c01376
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein, we report a direct phosphorylation of the C(sp(3))-H bond of 3,4-dihydroquinoxalin-2(1H)-ones using oxygen as a green oxidant under visible light at room temperature. This transformation was readily accomplished in the absence of metal and photosensitizer to construct new C(sp(3))-P bonds and provide a series of phosphonylated dihydroquinoxalin-2-ones in good to excellent yields. This approach opens straightforward and environmentally friendly access to 3-phosphoryl quinoxalin-2-ones derivatives.
引用
收藏
页码：11659 / 11664
页数：6
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