There is considerable uncertainty regarding the safety and efficacy of biological therapies during pregnancy. We report a case of a 46-year-old female, diagnosed with ulcerative colitis over 30 years ago, who was successfully managed with infliximab and ustekinumab. She experienced no exacerbation of her condition during two pregnancies, demonstrating the safety of biologic therapy in maintaining disease remission during pregnancy. This case report highlights successful outcomes despite the uncertainties associated with biologic therapy during pregnancy and includes a brief review of the relevant literature.
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Univ Chicago Med, Ctr Inflammatory Bowel Dis, 5841 South Maryland Ave,MC 4076, Chicago, IL 60637 USAUniv Chicago Med, Ctr Inflammatory Bowel Dis, 5841 South Maryland Ave,MC 4076, Chicago, IL 60637 USA
Sofia, M. Anthony
Rubin, David T.
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Univ Chicago Med, Ctr Inflammatory Bowel Dis, 5841 South Maryland Ave,MC 4076, Chicago, IL 60637 USAUniv Chicago Med, Ctr Inflammatory Bowel Dis, 5841 South Maryland Ave,MC 4076, Chicago, IL 60637 USA
机构:
Imelda GI Clinical Research Center, Imelda General Hospital, Department of Gastroenterology, 2820 BonheidenImelda GI Clinical Research Center, Imelda General Hospital, Department of Gastroenterology, 2820 Bonheiden
D'Haens G.
Daperno M.
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Imelda GI Clinical Research Center, Imelda General Hospital, Department of Gastroenterology, 2820 BonheidenImelda GI Clinical Research Center, Imelda General Hospital, Department of Gastroenterology, 2820 Bonheiden
机构:
Center for Crohn's and Colitis, University of California San Francisco, San Francisco, CA 94115Center for Crohn's and Colitis, University of California San Francisco, San Francisco, CA 94115
Velayos F.S.
Sandborn W.J.
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Center for Crohn's and Colitis, University of California San Francisco, San Francisco, CA 94115Center for Crohn's and Colitis, University of California San Francisco, San Francisco, CA 94115
机构:
Royal Prince Alfred Hosp, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Sydney, NSW, Australia
Connell, Alexander
Upendran, Yadhavan
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Royal Prince Alfred Hosp, Sydney, NSW, Australia
Univ Sydney, Cent Clin Sch, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Sydney, NSW, Australia
Upendran, Yadhavan
Lightowler, Daniel
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Royal Prince Alfred Hosp, Sydney, NSW, Australia
Univ Western Australia, Med Sch, Perth, WA, AustraliaRoyal Prince Alfred Hosp, Sydney, NSW, Australia
Lightowler, Daniel
Griffin, Sean
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Royal Prince Alfred Hosp, Sydney, NSW, Australia
Univ Sydney, Cent Clin Sch, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Sydney, NSW, Australia
Griffin, Sean
Corte, Crispin
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Royal Prince Alfred Hosp, Sydney, NSW, Australia
Univ Sydney, Cent Clin Sch, Sydney, NSW, AustraliaRoyal Prince Alfred Hosp, Sydney, NSW, Australia