Deadly nuts - detection of 3-nitropropionic acid in coconuts

被引：0
|
作者：
Westphal, K. Ringsborg [1 ]
Andersen, N. Vittrup [1 ]
Dideriksen, B. Uttrup [1 ]
Gunggaard, A. Filtenborg [1 ]
Duus, M. A. [1 ]
Sondergaard, T. E. [1 ]
机构：
[1] Dept Chem & Biosci, Fredrik Bajers Vej 7H, DK-9220 Aalborg, Denmark
来源：
WORLD MYCOTOXIN JOURNAL | 2024年 / 17卷 / 01期
关键词：
3-nitropropionic acid; coconuts; -1H NMR;
D O I：
10.1163/18750796-20232879
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
The secondary metabolite 3-nitropropionic acid (3-NPA) is produced by certain fungi. The metabolite is a potent toxin which inhibits the citric acid cycle. A medical case from 2021 described a 69-year-old Danish man who ingested 3-nitropropionic acid contaminated coconut water. The man died 26 hours after ingestion. Subsequent analysis identified Apiospora saccharicola as the fungi responsible for synthesising 3-NPA in the coconut. The metabolic pathway for 3-NPA is unknown but is thought to be activated by adverse growth conditions. This study aimed to confirm that Apiospora can produce 3-NPA within coconuts and develop a quick and easy method for detection of 3-NPA in coconut water using 1H NMR. This method can possibly aid in detection of 3-NPA in contaminated groceries, such as coconut water.
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页码：27 / 31
页数：5
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