Recent advances in food allergen immunotherapy

被引:1
|
作者
Jeon, You Hoon [1 ]
Kim, Edwin H. [2 ]
机构
[1] Hallym Univ, Dongtan Sacred Heart Hosp, Dept Pediat, Hwaseong, South Korea
[2] Univ North Carolina, Dept Pediat, Sch Med, 5004 Mary Ellen Jones Bldg,116 Manning Dr,CB 8035, Chapel Hill, NC 27599 USA
关键词
Food allergy; Oral immunotherapy; Sublingual immunotherapy; Epicutaneous immunotherapy; ORAL IMMUNOTHERAPY; PEANUT ALLERGY; EPICUTANEOUS IMMUNOTHERAPY; SUBLINGUAL IMMUNOTHERAPY; NATURAL-HISTORY; DOUBLE-BLIND; OPEN-LABEL; COWS MILK; CHILDREN; EFFICACY;
D O I
10.3345/cep.2023.01004
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Food allergies can pose significant risks and profoundly impact the quality of life of children and their families, making them a major public health concern. Allergen avoidance has been the traditional mainstay of treatment; however, recent research has focused on various approaches to food allergen immunotherapy. This review summarizes the recent advancements in oral, sublingual, and epicutaneous immunotherapies, highlighting their respective advantages and disadvantages. The ultimate goal of food allergen immunotherapy is to maximize efficacy while minimizing risks, leading to the exploration of strategies such as lowdose immunotherapy and the use of biologics. When selecting candidates for immunotherapy among patients with food allergies, factors such as allergen characteristics, the likelihood of natural resolution, age, symptom severity, and impact on quality of life require consideration, and an individualized approach should be adopted to determine the most suitable treatment method.
引用
收藏
页码:386 / 394
页数:9
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