BCG020, a novel bispecific antibody targeting EGFR and CD70, is effective against EGFR and CD70 high expressed tumors

被引：0
|
作者：
Yang, Yongfei
Sun, Xiaoxia
Li, Ziyan
Yan, Yue
Xu, Linpeng
Wu, Xiaoxue
Du, Luheng
Zhu, Ying
Guo, Chaoshe
An, W. Frank
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 06期
关键词：
D O I：
10.1158/1538-7445.AM2024-2724
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2724
引用
收藏
页数：2
相关论文
共 42 条
  • [21] CD70 antibody-drug conjugate: A novel therapeutic agent for platinum-resistant ovarian carcinoma
    Shiomi, Mayu
    Matsuzaki, Shinya
    Nakae, Ruriko
    Nakagawa, Satoshi
    Okazawa, Akiko
    Kobayashi, Eiji
    Ueda, Yutaka
    Serada, Satoshi
    Naka, Tetsuji
    Kimura, Tadashi
    CANCER RESEARCH, 2019, 79 (13)
  • [22] Targeting CD70 in cutaneous T-cell lymphoma using an antibody-drug conjugate, SGN-CD70A, in patient-derived xenograft models
    Zhuang, W. A. Ai
    Chi-Heng, W.
    Wang, L.
    Yang, C. Y.
    Wen, K. W.
    Hinds, B.
    Gill, R.
    McCormick, F.
    Moasser, M.
    Pincus, L.
    EUROPEAN JOURNAL OF CANCER, 2022, 173 : S17 - S17
  • [23] Effective IN VIVO Targeting of BCP-ALL in a NOD/SCID/huALL Mouse Model by CD70 Directed Immunotherapy
    Sun, Q.
    Debatin, K. -M.
    Meyer, L. H.
    ANNALS OF HEMATOLOGY, 2015, 94 (SUPPL 1) : 92 - 92
  • [24] Effective IN VIVO Targeting of BCP-ALL in a NOD/SCID/huALL Mouse Model by CD70 Directed Immunotherapy
    Sun, Q.
    Debatin, K. -M.
    Meyer, L. H.
    ANNALS OF HEMATOLOGY, 2015, 94 : S92 - S92
  • [25] Effective in Vivo Targeting of BCP-ALL in a NOD/SCID/huALL Mouse Model By CD70 Directed Immunotherapy
    Sun, Qian
    Borga, Chiara
    te Kronnie, Geertruy
    Debatin, Klaus-Michael
    Meyer, Lueder Hinrich
    BLOOD, 2014, 124 (21)
  • [26] TARGETING CD70 USING CAR-NK CELLS TO ENHANCE NK CELLS CYTOLYTIC EFFECT AGAINST OSTEOSARCOMA
    Ray, Emily
    Anjier, Ariana
    Acharya, Sunil
    Basar, Rafet
    Wang, Yifei
    Rezvani, Katy
    Gopalakrishnan, Vidya
    Gorlick, Richard
    Kleinerman, Eugenie
    Gordon, Nancy
    PEDIATRIC BLOOD & CANCER, 2022, 69
  • [27] Generation and Screening of Various CD70 CAR NK Cells Identify the Most Effective Construct Against Hematologic Malignancies
    Acharya, Sunil
    Basar, Rafet
    Daher, May
    Li, Ping
    Rafei, Hind
    Uprety, Nadima
    Ensley, Emily
    Shanley, Mayra
    Kumar, Bijender
    Banerjee, Pinaki
    Garcia, Luciana Melo
    Lin, Paul
    Mohanty, Vakul
    Pan, Yuchen
    Miao, Qi
    Kim, Kun Hee
    Jiang, Xianli
    Li, Ye
    Liu, Bin
    Cortes, Ana K. Nunez
    Zhang, Patrick
    Fathi, Mohsen
    Rezvan, Ali
    Montalvo, Melisa J.
    Liu, Enli
    Varadarajan, Navin
    Chen, Ken
    Marin, David
    Champlin, Richard E.
    Shpall, Elizabeth J.
    Rezvani, Katayoun
    BLOOD, 2023, 142
  • [28] EGFR, HLA-G, CD70, c-MET, and NY-ESO1 as potential biomarkers in high grade epithelial ovarian carcinoma
    Vo, Duc
    Liu, Yan
    Sood, Anil K.
    Rezvani, Katy
    Jazaeri, Amir A.
    Liu, Jinsong
    CANCER BIOMARKERS, 2024, 39 (04) : 289 - 298
  • [29] Potential Therapeutic Targets for Oral Cancer: ADM, TP53, EGFR, LYN, CTLA4, SKIL, CTGF, CD70
    Bundela, Saurabh
    Sharma, Anjana
    Bisen, Prakash S.
    PLOS ONE, 2014, 9 (07):
  • [30] CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual-targeting antibody overcome antigen heterogeneity in AML
    Silva, Harrison J.
    Martin, Grace
    Birocchi, Filippo
    Wehrli, Marc
    Kann, Michael C.
    Supper, Valentina
    Parker, Aiyana
    Graham, Charlotte
    Bratt, Alexandra
    Bouffard, Amanda
    Donner, Hannah
    Escobar, Giulia
    Takei, Hana
    Armstrong, Alexander
    Goncalves, Sadie
    Berger, Trisha R.
    Choi, Bryan D.
    Maus, Marcela, V
    Leick, Mark B.
    BLOOD, 2025, 145 (07) : 720 - 731
12345