Metabolic reprogramming enhances expansion and potency of CAR T cells

被引：0
|
作者：
Xing, Yewei
Eaker, Shannon
Bronevetsky, Yelena
Garcia, Candy
Lemar, Hadia
Massi, Evan
Wong, Albert
Barnes, Sheri
Germain, Derrik
Wise, Scott
Lim, James
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 06期
关键词：
D O I：
10.1158/1538-7445.AM2024-6334
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
6334
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Gut microbiota composition is predictive of CAR-T cells response and its modulation enhances CAR-T cells activity
    Marcos-Kovandzic, L.
    Rengassamy, J.
    Ferrere, G.
    Srikanthan, J.
    Durand, S.
    Derosa, L.
    Bigenwald, C.
    Zitvogel, L.
    ANNALS OF ONCOLOGY, 2024, 35 : S598 - S598
  • [42] Incorporation of functional elements enhances the antitumor capacity of CAR T cells
    Qin, Le
    Zhao, Ruocong
    Li, Peng
    EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2017, 6
  • [43] Incorporation of functional elements enhances the antitumor capacity of CAR T cells
    Le Qin
    Ruocong Zhao
    Peng Li
    Experimental Hematology & Oncology, 6
  • [44] FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
    Chan, Jack D.
    Scheffler, Christina M.
    Munoz, Isabelle
    Sek, Kevin
    Lee, Joel N.
    Huang, Yu-Kuan
    Yap, Kah Min
    Saw, Nicole Y. L.
    Li, Jasmine
    Chen, Amanda X. Y.
    Chan, Cheok Weng
    Derrick, Emily B.
    Todd, Kirsten L.
    Tong, Junming
    Dunbar, Phoebe A.
    Li, Jiawen
    Hoang, Thang X.
    de Menezes, Maria N.
    Petley, Emma V.
    Kim, Joelle S.
    Nguyen, Dat
    Leung, Patrick S. K.
    So, Joan
    Deguit, Christian
    Zhu, Joe
    House, Imran G.
    Kats, Lev M.
    Scott, Andrew M.
    Solomon, Benjamin J.
    Harrison, Simon J.
    Oliaro, Jane
    Parish, Ian A.
    Quinn, Kylie M.
    Neeson, Paul J.
    Slaney, Clare Y.
    Lai, Junyun
    Beavis, Paul A.
    Darcy, Phillip K.
    NATURE, 2024, 629 (8010) : 201 - 210
  • [45] Epigenetic reprogramming of CAR T cells for in vivo functional persistence against solid tumors
    Saitakis, Michael
    GENES AND IMMUNITY, 2024, 25 (05) : 434 - 436
  • [46] CONTEXTUAL REPROGRAMMING OF CAR T CELLS FOR THE TREATMENT OF HER2-EXPRESSING CANCERS
    Yang, Zhifen
    Li, Lingyu
    Turkoz, Ahu
    Chen, Pohan
    Choi, Hana
    Inel, Damla
    Qi, Stanley
    Marincola, Francesco
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A86 - A87
  • [47] Contextual reprogramming of CAR-T cells for treatment of HER2+ cancers
    Zhifen Yang
    Lingyu Li
    Ahu Turkoz
    Pohan Chen
    Rona Harari-Steinfeld
    Maggie Bobbin
    Ofir Stefanson
    Hana Choi
    Violena Pietrobon
    Bennett Alphson
    Angshumala Goswami
    Vitaly Balan
    Alper Kearney
    Dharmesh Patel
    Jin Yang
    Damla Inel
    Veena Vinod
    Alessandra Cesano
    Bing Wang
    Kyung-Ho Roh
    Lei S. Qi
    Francesco M. Marincola
    Journal of Translational Medicine, 19
  • [48] Contextual reprogramming of CAR-T cells for treatment of HER2+ cancers
    Yang, Zhifen
    Li, Lingyu
    Turkoz, Ahu
    Chen, Pohan
    Harari-Steinfeld, Rona
    Bobbin, Maggie
    Stefanson, Ofir
    Choi, Hana
    Pietrobon, Violena
    Alphson, Bennett
    Goswami, Angshumala
    Balan, Vitaly
    Kearney, Alper
    Patel, Dharmesh
    Yang, Jin
    Inel, Damla
    Vinod, Veena
    Cesano, Alessandra
    Wang, Bing
    Roh, Kyung-Ho
    Qi, Lei S.
    Marincola, Francesco M.
    JOURNAL OF TRANSLATIONAL MEDICINE, 2021, 19 (01)
  • [49] Logic gates controlled by priming receptors increase specificity and potency of CAR T cells
    Williams, Jasper
    Martinez, Kevin
    Boroughs, Angela
    Lim, Laura
    Sandoval, Marian
    Sue, Cate
    Drever, Matthew
    Yao, Anzhi
    Choe, Joseph
    Sidorov, Maxim
    Phillips, Sophia
    Polyak, Dina
    Mohanty, Suchismita
    Santoro, Stephen
    Cooper, Aaron
    Haining, W. Nicholas
    CANCER RESEARCH, 2022, 82 (12)
  • [50] QUALIFIABLE POTENCY ASSAY FOR CAR-T CELLS USING TWO SCALABLE PLATFORMS
    Kandell, J.
    Sylakowski, K.
    Lakshmipathy, U.
    CYTOTHERAPY, 2024, 26 (06) : S178 - S179
12345