Small molecule inhibitor of PELP1 exhibit cytotoxic effects on breast cancer cells by blocking ribosome biogenesis

被引：0
|
作者：
Yang, Xue
Nassar, Khaled Mohamed
Pratap, Uday
Gopalam, Rahul
Ebrahimi, Behnam
Panneerdoss, Durga Meenakshi
Li, Xiaonan
Yuan, Yaxia
Zhou, Daohong
Sareddy, Gangadhara R.
Tekmal, Rajeshwar R.
Rao, Manjeet
Viswanadhapalli, Suryavathi
Vadlamudi, Ratna
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 09期
关键词：
D O I：
10.1158/1538-7445.SABCS23-PO3-26-10
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
PO3-26-10
引用
收藏
页数：3
相关论文
共 50 条
  • [41] A small molecule, erbB kinase inhibitor blacks growth and invasion of human breast cancer cells and sensitizes them to ionizing radiation.
    Ignatoski, KMW
    Rao, G
    Ethier, SP
    CLINICAL CANCER RESEARCH, 1999, 5 : 3803S - 3803S
  • [42] Delivery of Small Molecule EF2 Kinase Inhibitor for Breast and Pancreatic Cancer Cells Using Hyaluronic Acid Based Nanogels
    Comert Onder, Ferah
    Sagbas Suner, Selin
    Sahiner, Nurettin
    Ay, Mehmet
    Ozpolat, Bulent
    PHARMACEUTICAL RESEARCH, 2020, 37 (03)
  • [43] Effect of a small-molecule MDM2/MDMX inhibitor on cell cycle arrest and apoptosis in breast cancer cells.
    Geng, Qian Qian
    Li, En Xiao
    Dong, Dan Feng
    Wu, Yin Ying
    Wang, Jie
    Li, Yi
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [44] Breast cancer cells can evade apoptosis-mediated selective killing by a novel small molecule inhibitor of Bcl-2
    Real, PJ
    Cao, YY
    Wang, RX
    Nikolovska-Coleska, Z
    Sanz-Ortiz, J
    Wang, SM
    Fernandez-Luna, JL
    CANCER RESEARCH, 2004, 64 (21) : 7947 - 7953
  • [45] Delivery of Small Molecule EF2 Kinase Inhibitor for Breast and Pancreatic Cancer Cells Using Hyaluronic Acid Based Nanogels
    Ferah Comert Onder
    Selin Sagbas Suner
    Nurettin Sahiner
    Mehmet Ay
    Bulent Ozpolat
    Pharmaceutical Research, 2020, 37
  • [46] The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells
    Wilson, Andrew J.
    Holson, Edward
    Wagner, Florence
    Zhang, Yan-Ling
    Fass, Daniel M.
    Haggarty, Stephen J.
    Bhaskara, Srividya
    Hiebert, Scott W.
    Schreiber, Stuart L.
    Khabele, Dineo
    CANCER BIOLOGY & THERAPY, 2011, 12 (06) : 484 - 493
  • [47] Examination of the effects of small molecule inhibitors of human histone lysine-specific demethylase I in breast cancer cells
    Pollock, Julie A.
    Larrea, Michelle D.
    McDonnell, Donald P.
    McCafferty, Dewey G.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
  • [48] Novel Small-Molecule Inhibitor for the Oncogenic Tyrosine Phosphatase SHP2 with Anti-Breast Cancer Cell Effects
    Hartman, Zachary
    Geldenhuys, Werner J.
    Agazie, Yehenew M.
    ACS OMEGA, 2020, 5 (39): : 25113 - 25124
  • [49] Characterization of a small molecule inhibitor for GD3 synthase (ST8SIA1), a novel target in breast cancer stem-like cells
    Jappupilli, Appalaraju
    Khoa Nguyen
    Ly, Stanley
    Andreeff, Michael
    Chelikani, Prashen
    Battula, Venkata Lokesh
    CANCER RESEARCH, 2019, 79 (13)
  • [50] 9-ING-41, a Small Molecule Inhibitor of GSK-3β, Potentiates the Effects of Chemotherapy on Colorectal Cancer Cells
    Poloznikov, Andrey
    Nikulin, Sergey
    Bolotina, Larisa
    Kachmazov, Andrei
    Raigorodskaya, Maria
    Kudryavtseva, Anna
    Bakhtogarimov, Ildar
    Rodin, Sergey
    Gaisina, Irina
    Topchiy, Maxim
    Asachenko, Andrey
    Novosad, Victor
    Tonevitsky, Alexander
    Alekseev, Boris
    FRONTIERS IN PHARMACOLOGY, 2021, 12
12345