Facilitating pathway and network based analysis of RNA-Seq data with pathlinkR

被引:0
|
作者
Blimkie, Travis M. [1 ]
An, Andy [1 ]
Hancock, Robert E. W. [1 ]
机构
[1] Univ British Columbia, Ctr Microbial Dis & Immun Res, Dept Microbiol & Immunol, REW Hancock Lab, Vancouver, BC, Canada
关键词
PACKAGE;
D O I
10.1371/journal.pcbi.1012422
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
R package pathlinkR is designed to aid transcriptomic analyses by streamlining and simplifying the process of analyzing and interpreting differentially expressed genes derived from human RNA-Seq data. It provides an integrated approach to performing pathway enrichment and network-based analyses, while also producing publication-quality figures to summarize these results, allowing users to more efficiently interpret their findings and extract biological meaning from large amounts of data. pathlinkR is available to install from the software repository Bioconductor at https://bioconductor.org/packages/pathlinkR/, with support available through the Bioconductor forums.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data
    Ge, Steven Xijin
    Son, Eun Wo
    Yao, Runan
    BMC BIOINFORMATICS, 2018, 19
  • [22] PathwaySplice: an R package for unbiased pathway analysis of alternative splicing in RNA-Seq data
    Yan, Aimin
    Ban, Yuguang
    Gao, Zhen
    Chen, Xi
    Wang, Lily
    BIOINFORMATICS, 2018, 34 (18) : 3220 - 3222
  • [23] Statistical Issues in the Analysis of ChIP-Seq and RNA-Seq Data
    Ghosh, Debashis
    Qin, Zhaohui S.
    GENES, 2010, 1 (02) : 317 - 334
  • [24] Oqtans: a multifunctional workbench for RNA-seq data analysis
    Sreedharan, Vipin T.
    Schultheiss, Sebastian J.
    Jean, Geraldine
    Kahles, Andre
    Bohnert, Regina
    Drewe, Philipp
    Mudrakarta, Pramod
    Goernitz, Nico
    Zeller, Georg
    Raetsch, Gunnar
    BMC BIOINFORMATICS, 2014, 15
  • [25] Differential expression analysis for paired RNA-seq data
    Chung, Lisa M.
    Ferguson, John P.
    Zheng, Wei
    Qian, Feng
    Bruno, Vincent
    Montgomery, Ruth R.
    Zhao, Hongyu
    BMC BIOINFORMATICS, 2013, 14 : 110
  • [26] Improving the Flexibility of RNA-Seq Data Analysis Pipelines
    Phan, John H.
    Wu, Po-Yen
    Wang, May D.
    2012 IEEE INTERNATIONAL WORKSHOP ON GENOMIC SIGNAL PROCESSING AND STATISTICS (GENSIPS), 2012, : 70 - 73
  • [27] Computational analysis of alternative polyadenylation from standard RNA-seq and single-cell RNA-seq data
    Gao, Yipeng
    Li, Wei
    MRNA 3' END PROCESSING AND METABOLISM, 2021, 655 : 225 - 243
  • [28] PUseqClust: A Clustering Analysis Method for RNA-Seq Data
    Shi X.-F.
    Liu X.-J.
    Zhang L.
    Ruan Jian Xue Bao/Journal of Software, 2019, 30 (09): : 2857 - 2868
  • [29] Multivariate approach to the analysis of correlated RNA-seq data
    Park, Hyunjin
    Lee, Seungyeoun
    Kim, Ye Jin
    Choi, Myung-Sook
    Park, Taesung
    2016 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM), 2016, : 1783 - 1786
  • [30] Intron Retention as a Mode for RNA-Seq Data Analysis
    Zheng, Jian-Tao
    Lin, Cui-Xiang
    Fang, Zhao-Yu
    Li, Hong-Dong
    FRONTIERS IN GENETICS, 2020, 11