Management of Clostridioides difficile Infection: Diagnosis, Treatment, and Future Perspectives

被引：5

作者：

Cymbal, Michael ^{[1
]}

Chatterjee, Arjun ^{[1
]}

Baggott, Brian ^{[2
]}

Auron, Moises ^{[3
,4
]}

机构：

[1] Cleveland Clin, Dept Internal Med, Cleveland, OH USA

[2] Cleveland Clin, Dept Gastroenterol Hepatol & Nutr, Cleveland, OH USA

[3] Cleveland Clin, Dept Hosp Med, Cleveland, OH USA

[4] Outcomes Res Consortium, Cleveland, OH USA

来源：

AMERICAN JOURNAL OF MEDICINE | 2024年 / 137卷 / 07期

关键词：

Clostridioides difficile; C; diff; Pseudomembranous colitis; HEALTH-CARE EPIDEMIOLOGY; DISEASES SOCIETY; AMERICA IDSA; GUIDELINES; UPDATE;

D O I：

10.1016/j.amjmed.2024.03.024

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clostridioides difficile infection is the most common healthcare-associated infection in the United States, with potential life-threatening complications and a significant impact on the costs of care. Antibiotic stewardship as well as discontinuation of chronic acid suppressive therapy are key for its prevention and treatment. Effective infection management requires appropriate interpretation of diagnostic tests, as well as the use of vancomycin and fidaxomicin as first-line treatment. Novel treatments such as Bezlotoxumab, fecal microbiota transplant, and live biotherapeutic products are proven effective in recurrent C. difficile infection and address dysbiosis. (c) 2024 The Authors. Published by Elsevier Inc. CCBYLICENSE This is an open access article under the (2024) 137:571-576

引用

页码：571 / 576

页数：6

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