An Interesting Case of Alpha-Fetoprotein (AFP)Producing Pancreaticoduodenal Tumor

被引:0
|
作者
Gvajaia, Ani [1 ]
Imeh, Michael [1 ]
Raza, Ali [2 ]
机构
[1] NYCHHC, Internal Med, Weill Cornell Med Coll, Lincoln Med & Mental Hlth Ctr, Bronx, NY 10451 USA
[2] NYCHHC, Weill Cornell Medical Coll, Lincoln Med & Mental Hlth Ctr, Surg Oncol, Bronx, NY USA
关键词
GASTRIC-CANCER; EXPRESSION; CARCINOMA; CELLS;
D O I
10.7759/cureus.59384
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Alpha-fetoprotein (AFP) is considered one of the best-known predictive serum markers, playing a crucial role in cancer investigation and subsequent treatment. In most adult cells, the production of this marker is suppressed after embryogenesis. However, its increased level raises concerns about underlying malignant conditions, which provide a valuable diagnostic tool for medical professionals in oncology. The existing AFP-producing adenocarcinomas exhibit unique clinical characteristics, including high malignancy and early metastatic potential, which result in poorer outcomes. To illustrate these characteristics, we decided to describe a case report of a 70 -year -old African American female with a significantly elevated level of AFP. Further pathology results confirmed a duodenal adenocarcinoma versus adenocarcinoma from the pancreas. While AFP-producing adenocarcinoma has multiple underlying molecular mechanisms that correlate with poor prognosis, definitive treatment based on molecular pathways has yet to be defined. Therefore, further research is needed for new therapeutic modalities.
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页数:9
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