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Impact of bariatric surgery on circulating irisin levels: a systematic review and meta-analysis
被引:1
|作者:
Jamialahamdi, Tannaz
[1
,2
]
Mirhadi, Elaheh
[3
]
Almahmeed, Wael
[4
]
Eid, Ali H.
[5
]
Al-Rasadi, Khalid
[6
,7
]
Nguyen, Ninh T.
[8
]
Gadde, Kishore M.
[8
]
Sahebkar, Amirhossein
[9
,10
,11
]
机构:
[1] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Pharmaceut Res Ctr, Mashhad, Iran
[2] Mashhad Univ Med Sci, Med Toxicol Res Ctr, Mashhad, Iran
[3] Mashhad Univ Med Sci, Sch Pharm, Mashhad, Iran
[4] Cleveland Clin Abu Dhabi, Heart & Vasc Inst, Abu Dhabi, U Arab Emirates
[5] Qatar Univ, QU Hlth, Coll Med, Dept Basic Med Sci, Doha, Qatar
[6] Sultan Qaboos Univ, Med Res Ctr, Muscat, Oman
[7] Sultan Qaboos Univ, Coll Med & Hlth Sci, Dept Biochem, Muscat, Oman
[8] Univ Calif Irvine, Med Ctr, Dept Surg, Orange, CA USA
[9] Saveetha Univ, Saveetha Med Coll & Hosp, Saveetha Inst Med & Tech Sci, Chennai, India
[10] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Biotechnol Res Ctr, Mashhad, Iran
[11] Mashhad Univ Med Sci, Appl Biomed Res Ctr, Mashhad, Iran
关键词:
Bariatric surgery;
Irisin levels;
Roux-en-Y gastric bypass;
Sleeve gastrectomy;
FNDC5;
EXPRESSION;
WEIGHT;
D O I:
10.1007/s13304-024-01866-8
中图分类号:
R61 [外科手术学];
学科分类号:
摘要:
This systematic review and meta-analysis evaluated changes in circulating irisin levels after bariatric surgery. A systematic search was performed across Embase, Scopus, PubMed, and Web of Science for this study. The meta-analysis was conducted using Comprehensive Meta-Analysis (CMA) V4 software. The overall effect size was depicted through a random-effects meta-analysis and the leave-one-out method. The meta-analysis, which included 13 studies with a total of 407 participants, showed a statistically non-significant reduction in circulating irisin levels following bariatric surgery (SMD: - 0.089, 95% CI - 0.281, 0.102, 95% PI: - 0.790, 0.611, p = 0.360; I2:70.56). Our research found no significant change in irisin levels after bariatric surgery. Moreover, these findings were not associated with the type of surgery or the duration of follow-up.
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页码:2745 / 2754
页数:10
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