Advanced Convolutional Neural Networks for Precise White Blood Cell Subtype Classification in Medical Diagnostics

被引:2
|
作者
Kanavos, Athanasios [1 ]
Papadimitriou, Orestis [1 ]
Al-Hussaeni, Khalil [2 ]
Maragoudakis, Manolis [3 ]
Karamitsos, Ioannis [4 ]
机构
[1] Univ Aegean, Dept Informat & Commun Syst Engn, Samos 83200, Greece
[2] Rochester Inst Technol, Comp Sci Dept, Dubai 341055, U Arab Emirates
[3] Ionian Univ, Dept Informat, Corfu 49100, Greece
[4] Rochester Inst Technol, Grad & Res Dept, Dubai 341055, U Arab Emirates
关键词
convolutional neural networks (CNN); deep learning; disease diagnosis; feature extraction; image classification; image segmentation; white blood cells (WBCs); medical image analysis; PROGNOSIS;
D O I
10.3390/electronics13142818
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
White blood cell (WBC) classification is pivotal in medical image analysis, playing a critical role in the precise diagnosis and monitoring of diseases. This paper presents a novel convolutional neural network (CNN) architecture designed specifically for the classification of WBC images. Our model, trained on an extensive dataset, automates the extraction of discriminative features essential for accurate subtype identification. We conducted comprehensive experiments on a publicly available image dataset to validate the efficacy of our methodology. Comparative analysis with state-of-the-art methods shows that our approach significantly outperforms existing models in accurately categorizing WBCs into their respective subtypes. An in-depth analysis of the features learned by the CNN reveals key insights into the morphological traits-such as shape, size, and texture-that contribute to its classification accuracy. Importantly, the model demonstrates robust generalization capabilities, suggesting its high potential for real-world clinical implementation. Our findings indicate that the proposed CNN architecture can substantially enhance the precision and efficiency of WBC subtype identification, offering significant improvements in medical diagnostics and patient care.
引用
收藏
页数:24
相关论文
共 50 条
  • [31] Ensemble Convolutional Neural Networks for Cell Classification in Microscopic Images
    Shi, Tian
    Wu, Longshi
    Zhong, Changhong
    Wang, Ruixuan
    Zheng, Weishi
    ISBI 2019 C-NMC CHALLENGE: CLASSIFICATION IN CANCER CELL IMAGING, 2019, : 43 - 51
  • [32] Application of Convolutional Neural Networks for Diagnostics of Tuberculosis
    Grivkov, A., V
    Smirnov, A. A.
    VII INTERNATIONAL YOUNG RESEARCHERS' CONFERENCE - PHYSICS, TECHNOLOGY, INNOVATIONS (PTI-2020), 2020, 2313
  • [33] Classification of Blood Cancer Images Using a Convolutional Neural Networks Ensemble
    Ma, Kaiqiang
    Sun, Lingling
    Wang, Yaqi
    Wang, Junchao
    ELEVENTH INTERNATIONAL CONFERENCE ON DIGITAL IMAGE PROCESSING (ICDIP 2019), 2019, 11179
  • [34] Optimization-based convolutional neural model for the classification of white blood cells
    Devi, Tulasi Gayatri
    Patil, Nagamma
    JOURNAL OF BIG DATA, 2024, 11 (01)
  • [35] Machine learning using convolutional neural networks for SERS analysis of biomarkers in medical diagnostics
    Li, Joy Qiaoyi
    Dukes, Priya Vohra
    Lee, Walter
    Sarkis, Michael
    Vo-Dinh, Tuan
    JOURNAL OF RAMAN SPECTROSCOPY, 2022, 53 (12) : 2044 - 2057
  • [36] White Blood Cells Classification Using Convolutional Neural Network Hybrid System
    Malkawi, Areej
    Al-Assi, Rawan
    Salameh, Taimaa
    Sheyab, Baraah
    Alquran, Hiam
    Alqudah, Ali Mohmnmad
    2020 IEEE 5TH MIDDLE EAST AND AFRICA CONFERENCE ON BIOMEDICAL ENGINEERING (MECBME), 2020, : 43 - 47
  • [37] Breast cancer diagnostics by the intelligent analysis of white blood cells' interaction with target cancer cells using convolutional neural networks
    Khayamian, Mohammad Ali
    Parizi, Mohammad Salemizadeh
    Vanaei, Shohreh
    Ghaderinia, Mohammadreza
    Abadijoo, Hamed
    Shalileh, Shahriar
    Saghafi, Mohammad
    Simaee, Hossein
    Abbasvandi, Fereshteh
    Akbari, Navid
    Karimi, Arash
    Sanati, Hassan
    Sarrami-Forooshani, Ramin
    Abdolahad, Mohammad
    MICROCHEMICAL JOURNAL, 2024, 205
  • [38] White blood cell classification using multi-hop attention graph neural networks
    Duc, Minh Ly
    Bilik, Petr
    Martinek, Radek
    EXPERT SYSTEMS WITH APPLICATIONS, 2025, 272
  • [39] Red blood cell classification in lensless single random phase encoding using convolutional neural networks
    O'Connor, Timothy
    Hawxhurst, Christopher
    Shor, Leslie M.
    Javidi, Bahram
    OPTICS EXPRESS, 2020, 28 (22): : 33504 - 33515
  • [40] Convolutional Neural Networks for event classification
    Rubio Jimenez, Adrian
    Garcia Navarro, Jose Enrique
    Moreno Llacer, Maria
    NINTH ANNUAL CONFERENCE ON LARGE HADRON COLLIDER PHYSICS, LHCP2021, 2021,