Multi-layered effects of Panax notoginseng on immune system

被引：1
|
作者：
Yang, Chunhao [1 ,2 ]
Qu, Liping [1 ,2 ,3 ]
Wang, Rui [1 ,2 ]
Wang, Feifei [1 ,2 ,3 ]
Yang, Zhaoxiang [1 ,2 ]
Xiao, Fengkun [1 ,2 ]
机构：
[1] Yunnan Yunke Characterist Plant Extract Lab Co Ltd, Yunnan Characterist Plant Extract Lab, Kunming 650106, Peoples R China
[2] Yunnan Botanee Biotechnol Grp Co Ltd, Kunming 650106, Peoples R China
[3] Shanghai Jiyan Biomed Dev Co Ltd, Botanee Res Inst, Innovat Mat Res & Dev Ctr, Shanghai 201702, Peoples R China
来源：
PHARMACOLOGICAL RESEARCH | 2024年 / 204卷
关键词：
Panax notoginseng; immunomodulatory efficiency; leucocyte; METABOLITE COMPOUND K; INDUCED MICROCIRCULATORY DISTURBANCE; DENDRITIC CELL SUBSETS; NF-KAPPA-B; GINSENOSIDE RG1; NMDA RECEPTORS; SAPONINS PNS; MAST-CELLS; T-CELLS; RESPONSES;
D O I：
10.1016/j.phrs.2024.107203
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Recent research has demonstrated the immunomodulatory potential of Panax notoginseng in the treatment of chronic inflammatory diseases and cerebral hemorrhage, suggesting its significance in clinical practice. Nevertheless, the complex immune activity of various components has hindered a comprehensive understanding of the immune-regulating properties of Panax notoginseng, impeding its broader utilization. This review evaluates the effect of Panax notoginseng to various types of white blood cells, elucidates the underlying mechanisms, and compares the immunomodulatory effects of different Panax notoginseng active fractions, aiming to provide the theory basis for future immunomodulatory investigation.
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页数：18
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