Nanoparticles in cancer diagnosis and treatment: Progress, challenges, and opportunities

被引:13
|
作者
Rashidi, Niloufar [1 ]
Davidson, Majid [1 ,2 ]
Apostolopoulos, Vasso [1 ,3 ]
Nurgali, Kulmira [1 ,2 ,4 ]
机构
[1] Victoria Univ, Inst Hlth & Sport, Melbourne, Australia
[2] Australian Inst Musculoskeletal Sci AIMSS, Regenerat Med & Stem Cells Program, Melbourne, Australia
[3] Australian Inst Musculoskeletal Sci AIMSS, Immunol Program, Melbourne, Australia
[4] Univ Melbourne, Fac Med Dent & Hlth Sci, Dept Med Western Hlth, Melbourne, Australia
关键词
Nanoparticles; Cancer treatment; Drug delivery; Nanomedicine; Clinical trials; PEGYLATED LIPOSOMAL DOXORUBICIN; METASTATIC BREAST-CANCER; DRUG-DELIVERY SYSTEMS; GOLD NANOPARTICLES; RADIATION-THERAPY; PHASE-I; MESOPOROUS SILICA; QUANTUM DOTS; TUMOR-CELLS; CO-DELIVERY;
D O I
10.1016/j.jddst.2024.105599
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Despite considerable progress in patient care, the global incidence of various cancer types continues to rise. Developing safer and more efficient anti -cancer treatment approaches are of great interest. In recent decades, nanotechnology has emerged as a promising and innovative medical approach for cancer diagnosis and treatment. However, as nanomedicine for cancer advances, it is important to understand and address challenges. Herein, we identify gaps in the current understanding of the effectiveness of nanomedicine on clinical outcomes and provide an outlook for the improved application of nanotechnology in medicine. We discuss the use of different types of nanoparticles for cancer diagnosis and therapy and the impact of the use of nanoparticles on the efficiency of existing anti -cancer treatments, such as chemotherapeutic, anti-angiogenic, immunotherapeutic drugs, and radiotherapy. Additionally, an update on the current status of clinical trials for nanoparticle-based treatments is provided.
引用
收藏
页数:15
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