Multi-Point Sensing via Organic Optical Fibres for FLASH Proton Therapy

被引:0
|
作者
Penner, Crystal [1 ,2 ,3 ]
Usherovich, Samuel [1 ]
Andru, Sophia [1 ]
Belanger-Champagne, Camille [1 ]
Hohnholz, Janina [1 ,4 ]
Stoeber, Boris [3 ]
Duzenli, Cheryl [2 ]
Hoehr, Cornelia [1 ]
机构
[1] TRIUMF, Life Sci Div, 4004 Wesbrook Mall, Vancouver, BC V6T 2A3, Canada
[2] BC Canc, 600 West 10th Ave, Vancouver, BC V5Z 4E6, Canada
[3] Univ British Columbia, Dept Elect & Comp Engn, 2332 Main Mall, Vancouver, BC V6T 1Z4, Canada
[4] FH Aachen Univ Appl Sci, Dept Chem & Biotechnol, Heinrich Mussmann Str 1, D-52428 Julich, Germany
关键词
optical fibre scintillator; FLASH radiotherapy; proton FLASH; multipoint; fibre array; proton radiotherapy; multipixel photon counter; photodetector; IRRADIATION;
D O I
10.3390/electronics13112211
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Optical fibres are gaining popularity for relative dosimetry in proton therapy due to their spatial resolution and ability for near real-time acquisition. For FLASH proton therapy, these fibres need to handle higher dose rates and larger doses than for conventional proton dose rates. We developed a multi-point fibre sensor embedded in a 3D-printed phantom which can measure the profile of a FLASH proton beam. Seven PMMA fibres of 1 mm diameter were embedded in a custom 3D-printed plastic phantom of the same density as the fibres. The phantom was placed in a proton beam with FLASH dose rates at the TRIUMF Proton Therapy Research Centre (PTRC). The sensor was exposed to different proton energies, 13.5 MeV, 19 MeV and 40.4 MeV, achieved by adding PMMA bolus in front of the phantom and three different beam currents, varying the dose rates from 7.5 to 101 Gy/s. The array was able to record beam profiles in both transverse and axial directions in relative agreement with measurements from EBT-XD radiochromic films (transverse) and Monte Carlo simulations (axial). A decrease in light output over time was observed, which might be caused by radiation damage in the matrix of the fibre and characterised by an exponential decay function.
引用
收藏
页数:13
相关论文
共 50 条
  • [41] Two-function light source in a FBG multi-point sensing system
    HE Shi-ya
    Optoelectronics Letters, 2007, (03) : 219 - 221
  • [42] Two-function light source in a FBG multi-point sensing system
    He S.-Y.
    Deng Y.-H.
    Yu Y.
    Hu S.-Y.
    Guan Z.
    Optoelectronics Letters, 2007, 3 (3) : 219 - 221
  • [43] Multi-point temperature sensing using a linear-cavity lasing system
    Kishikawa, Hiroki
    Okada, Mao
    Takahashi, Kazuto
    Chen, Po-Jung
    Goto, Nobuo
    Yu, Yi-Lin
    Liaw, Shien-Kuei
    APPLIED OPTICS, 2017, 56 (11) : 3206 - 3212
  • [44] Bayesian Optimization for Antenna Design via Multi-Point Active Learning
    Wang, Mei
    Zhu, Yi
    Li, Haitao
    Zhou, Jinzhu
    Wang, Pingan
    2020 IEEE MTT-S INTERNATIONAL CONFERENCE ON NUMERICAL ELECTROMAGNETIC AND MULTIPHYSICS MODELING AND OPTIMIZATION (NEMO 2020), 2020,
  • [45] MULTI-POINT THERMAL SENSING NEEDLES: IMPROVED ONCOLOGICAL OUTCOMES FOLLOWING CRYOABLATION
    Martin, Jeremy W.
    Patel, Roshan
    Okhunov, Zhamshid
    Vyas, Aashay
    Landman, Jaime
    Vajgrt, Duane
    Clayman, Ralph V.
    JOURNAL OF UROLOGY, 2017, 197 (04): : E1330 - E1330
  • [46] Multi-Point Vehicular Positioning via Millimeter-Wave Transmissions
    Zhang, Zezhong
    Ko, Seung-Woo
    Wang, Rui
    Huang, Kaibin
    2019 34TH INTERNATIONAL TECHNICAL CONFERENCE ON CIRCUITS/SYSTEMS, COMPUTERS AND COMMUNICATIONS (ITC-CSCC 2019), 2019, : 506 - 509
  • [47] Point to multi-point physical-layer key generation and distribution in passive optical networks
    Zhang, Liuming
    Huang, Xinran
    Hu, Weisheng
    Yang, Xuelin
    OPTICS LETTERS, 2021, 46 (13) : 3223 - 3226
  • [48] Multi-point optical focusing based on enhanced multi-objective optimized wavefront shaping
    Hu, Yue
    Hu, Minglong
    Zhou, Junjie
    Ding, Yingchun
    OPTICS COMMUNICATIONS, 2023, 547
  • [49] Elimination of Laser Power Loss Influence for Multi-Point Gas Sensing in Photoacoustic Spectroscopy
    Qian, Siyu
    Tian, Cunwei
    Wang, Zongliang
    Yu, Yuanfang
    Bi, Shaoqiang
    Zhang, XiuKun
    IEEE SENSORS JOURNAL, 2021, 21 (09) : 10571 - 10578
  • [50] Analysis of Carbon Dioxide Concentration in a Room of Multiple Persons by Simultaneous Multi-Point Sensing
    Watanabe, Norifumi
    Moritani, Motokazu
    2020 IEEE INTERNATIONAL CONFERENCE ON SYSTEMS, MAN, AND CYBERNETICS (SMC), 2020, : 3768 - 3775