Multi-Point Sensing via Organic Optical Fibres for FLASH Proton Therapy

被引:0
|
作者
Penner, Crystal [1 ,2 ,3 ]
Usherovich, Samuel [1 ]
Andru, Sophia [1 ]
Belanger-Champagne, Camille [1 ]
Hohnholz, Janina [1 ,4 ]
Stoeber, Boris [3 ]
Duzenli, Cheryl [2 ]
Hoehr, Cornelia [1 ]
机构
[1] TRIUMF, Life Sci Div, 4004 Wesbrook Mall, Vancouver, BC V6T 2A3, Canada
[2] BC Canc, 600 West 10th Ave, Vancouver, BC V5Z 4E6, Canada
[3] Univ British Columbia, Dept Elect & Comp Engn, 2332 Main Mall, Vancouver, BC V6T 1Z4, Canada
[4] FH Aachen Univ Appl Sci, Dept Chem & Biotechnol, Heinrich Mussmann Str 1, D-52428 Julich, Germany
关键词
optical fibre scintillator; FLASH radiotherapy; proton FLASH; multipoint; fibre array; proton radiotherapy; multipixel photon counter; photodetector; IRRADIATION;
D O I
10.3390/electronics13112211
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Optical fibres are gaining popularity for relative dosimetry in proton therapy due to their spatial resolution and ability for near real-time acquisition. For FLASH proton therapy, these fibres need to handle higher dose rates and larger doses than for conventional proton dose rates. We developed a multi-point fibre sensor embedded in a 3D-printed phantom which can measure the profile of a FLASH proton beam. Seven PMMA fibres of 1 mm diameter were embedded in a custom 3D-printed plastic phantom of the same density as the fibres. The phantom was placed in a proton beam with FLASH dose rates at the TRIUMF Proton Therapy Research Centre (PTRC). The sensor was exposed to different proton energies, 13.5 MeV, 19 MeV and 40.4 MeV, achieved by adding PMMA bolus in front of the phantom and three different beam currents, varying the dose rates from 7.5 to 101 Gy/s. The array was able to record beam profiles in both transverse and axial directions in relative agreement with measurements from EBT-XD radiochromic films (transverse) and Monte Carlo simulations (axial). A decrease in light output over time was observed, which might be caused by radiation damage in the matrix of the fibre and characterised by an exponential decay function.
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页数:13
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