diplopia;
hilar lymphadenopathy;
uveitis;
rare cause of dysphagia;
antidiuretic hormone and neurosarcoidosis;
atypical sarcoid;
D O I:
10.7759/cureus.60146
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Sarcoidosis is a multisystem granulomatous disorder with an unknown etiology that typically involves the lungs, skin, and lymph nodes, with neurological involvement being relatively rare. We discuss a case of neurosarcoidosis in a 64-year-old man who initially presented with unexplained cognitive impairment, insomnia, hyponatremia, paresthesias, and weight loss and later developed uveitis, diplopia, and dysphagia. Ultimately, findings of hilar and mediastinal lymphadenopathy on chest computed tomography (CT) resulted in bronchoscopy, which led to the diagnosis. This case highlights a rare presentation of sarcoidosis with an unusual constellation of symptoms. We discuss the difficulty involved in diagnosing this disorder as well as its highly variable course.
机构:
Univ Utah Hlth, Dept Internal Med, Salt Lake City, UT USAUniv Utah Hlth, Dept Internal Med, Salt Lake City, UT USA
Werst, Dylan
Scarpato, Brittany
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机构:
Univ Utah Hlth, Div Pulm & Crit Care Med, Salt Lake City, UT 84132 USAUniv Utah Hlth, Dept Internal Med, Salt Lake City, UT USA
Scarpato, Brittany
Callahan, Sean J.
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机构:
Univ Utah Hlth, Div Pulm & Crit Care Med, Salt Lake City, UT 84132 USA
George E Wahlen VA Med Ctr, Salt Lake City, UT USAUniv Utah Hlth, Dept Internal Med, Salt Lake City, UT USA
Callahan, Sean J.
Scholand, Mary Beth
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机构:
Univ Utah Hlth, Div Pulm & Crit Care Med, Salt Lake City, UT 84132 USAUniv Utah Hlth, Dept Internal Med, Salt Lake City, UT USA
机构:
Nippon Med Sch, Dept Analyt Human Pathol, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Endo, Yoko
Ohashi, Ryuji
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机构:
Nippon Med Coll Hosp, Dept Diagnost Pathol, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Ohashi, Ryuji
Inai, Shunta
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机构:
Nippon Med Sch, Dept Otolaryngol Head & Neck Surg, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Inai, Shunta
Yokoshima, Kazuhiko
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机构:
Nippon Med Sch, Dept Otolaryngol Head & Neck Surg, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Yokoshima, Kazuhiko
Nakamizo, Munenaga
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机构:
Nippon Med Sch, Dept Otolaryngol Head & Neck Surg, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Nakamizo, Munenaga
Shimizu, Akira
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机构:
Nippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Nippon Med Coll Hosp, Dept Diagnost Pathol, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Shimizu, Akira
Okubo, Kimihiro
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机构:
Nippon Med Sch, Dept Otolaryngol Head & Neck Surg, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
Okubo, Kimihiro
Naito, Zenya
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机构:
Nippon Med Coll Hosp, Dept Diagnost Pathol, Tokyo, Japan
Nippon Med Sch, Dept Integrated Diagnost Pathol, Tokyo, JapanNippon Med Sch, Dept Analyt Human Pathol, Tokyo, Japan
机构:
Mayo Clin, Sch Grad Med Educ, Internal Med, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Internal Med, Rochester, MN USA
Schmidt, Tyler J.
Subat, Yosuf W.
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机构:
Mayo Clin, Sch Grad Med Educ, Pulm & Crit Care Med, Rochester, MN USA
Mayo Clin, Sch Grad Med Educ, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Internal Med, Rochester, MN USA
Subat, Yosuf W.
De Moraes, Alice Gallo
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机构:
Mayo Clin, Pulm & Crit Care Med, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Internal Med, Rochester, MN USA