Progression-free survival end points in prostate cancer: are we truly making progress

被引：1
|
作者：
Madan, Ravi A. [1 ]
Posadas, Edwin M. [2 ]
Lee, Richard J. [3 ]
机构：
[1] NCI, Genitourinary Malignancies Branch, Bethesda, MD 20892 USA
[2] Samuel Oschin Comprehens Canc Inst, Cedars Sinai Med Ctr, Los Angeles, CA USA
[3] Harvard Med Sch, Massachusetts Gen Hosp, Canc Ctr, Dept Med, Boston, MA USA
来源：
NATURE REVIEWS UROLOGY | 2024年 / 21卷 / 11期
关键词：
PHASE-III; PREDNISONE; CABOZANTINIB; DOCETAXEL; 2ND;
D O I：
10.1038/s41585-024-00902-x
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Recently, several therapeutic strategies in prostate cancer have been granted regulatory approval based on progression-free survival benefits alone, which is a relative change in the therapeutic development of prostate cancer treatments. Previously, overall survival was a requirement for approvals. Whether this approach is warranted or beneficial to patients remains unclear.
引用
收藏
页码：646 / 648
页数：3
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