Prostate cancer, a prevalent malignancy affecting the prostate gland, is a significant global health concern. Androgen-deprivation therapy (ADT) has proven effective in controlling advanced disease, with over 50% of patients surviving at the 10-year mark. However, a diverse spectrum of responses exists, and resistance to ADT may emerge over time. This underscores the need to explore innovative treatment strategies for effectively managing prostate cancer progression. Ongoing research endeavors persist in unraveling the complexity of prostate cancer and fostering the development of biologic and innovative approaches, including immunotherapies and targeted therapies. This review aims to provide a valuable synthesis of the dynamic landscape of emerging drug modalities in this context. Interestingly, the complexities posed by prostate cancer not only present a formidable challenge but also serve as a model and an opportunity for translational research and innovative therapies in the field of oncology.
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Univ Colorado, Hlth Sci Ctr, UCDSOM, Div Urol, Acad Off 1 Bldg 12631 E 17th Ave Room L15-5602,MS, Aurora, CO 80045 USAUniv Colorado, Hlth Sci Ctr, UCDSOM, Div Urol, Acad Off 1 Bldg 12631 E 17th Ave Room L15-5602,MS, Aurora, CO 80045 USA
Hou, A. H.
Swanson, D.
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Univ Colorado, Hlth Sci Ctr, UCDSOM, Div Urol, Acad Off 1 Bldg 12631 E 17th Ave Room L15-5602,MS, Aurora, CO 80045 USAUniv Colorado, Hlth Sci Ctr, UCDSOM, Div Urol, Acad Off 1 Bldg 12631 E 17th Ave Room L15-5602,MS, Aurora, CO 80045 USA
Swanson, D.
Barqawi, A. B.
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Univ Colorado, Hlth Sci Ctr, UCDSOM, Div Urol, Acad Off 1 Bldg 12631 E 17th Ave Room L15-5602,MS, Aurora, CO 80045 USAUniv Colorado, Hlth Sci Ctr, UCDSOM, Div Urol, Acad Off 1 Bldg 12631 E 17th Ave Room L15-5602,MS, Aurora, CO 80045 USA
机构:
Lund Univ, Clin Res Ctr Malmo, Dept Lab Med, Div Expt Canc Res, S-22100 Lund, SwedenLund Univ, Clin Res Ctr Malmo, Dept Lab Med, Div Expt Canc Res, S-22100 Lund, Sweden
Semenas, Julius
Allegrucci, Cinzia
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Univ Nottingham, Sch Vet Med & Sci, Fac Med & Hlth Sci, Loughborough LE12 5RD, Leics, EnglandLund Univ, Clin Res Ctr Malmo, Dept Lab Med, Div Expt Canc Res, S-22100 Lund, Sweden
Allegrucci, Cinzia
Boorjian, Stephen A.
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Mayo Clin, Dept Urol, Rochester, MN USALund Univ, Clin Res Ctr Malmo, Dept Lab Med, Div Expt Canc Res, S-22100 Lund, Sweden
Boorjian, Stephen A.
Mongan, Nigel P.
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Univ Nottingham, Sch Vet Med & Sci, Fac Med & Hlth Sci, Loughborough LE12 5RD, Leics, EnglandLund Univ, Clin Res Ctr Malmo, Dept Lab Med, Div Expt Canc Res, S-22100 Lund, Sweden
Mongan, Nigel P.
Persson, Jenny Liao
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Lund Univ, Clin Res Ctr Malmo, Dept Lab Med, Div Expt Canc Res, S-22100 Lund, SwedenLund Univ, Clin Res Ctr Malmo, Dept Lab Med, Div Expt Canc Res, S-22100 Lund, Sweden