Microwave Assisted Grafting Technique for Modification of Polysaccharides

被引:1
|
作者
Rajpoot, Neetu [1 ]
Puri, Dinesh [1 ]
机构
[1] Graph Era Hill Univ, Sch Pharm, Dehra Dun, Uttarakhand, India
关键词
Grafting technique; microwave; pharmaceutical formulations; polysaccharide; macro-molecules; polymers; CONTROLLED DELIVERY; INITIATED SYNTHESIS; MUCOADHESIVE BEADS; PHYSICOCHEMICAL PROPERTIES; CONTROLLED-RELEASE; ORGANIC-SYNTHESIS; G-PAM; STARCH; COPOLYMERIZATION; CHITOSAN;
D O I
10.2174/0113852728296687240328080900
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A natural and renewable substrate for the synthesis of high-performance macromolecules is polysaccharides. Grafting with the use of microwaves of synthetic polymers onto natural polysaccharides is a common, adaptable, and practical method of creating materials based on polysaccharides. It eliminates all drawbacks of the traditional grafting technique, including the need for hazardous solvents and longer reaction times. Grafting yield is also increased by microwave irradiation. In fact, the employment of microwaves in polysaccharide grafting modification for diverse applications has been prompted by the growing interest in clean and environment-friendly chemistry. Furthermore, compared with their traditionally synthesized counterparts, microwave-synthesized polysaccharide copolymers frequently have greater characteristics for commercial exploitation. Moreover, for many traditional grafting processes, the necessity for an inert environment is an additional drawback, which can be overcome by microwave grafting techniques. This study focuses on the current use of microwave heating in polysaccharide grafting modifications and its further use in pharmaceutical formulations.
引用
收藏
页码:844 / 856
页数:13
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