Full decongestion in acute heart failure therapy

被引:0
|
作者
Buttar, Chandan [1 ,2 ]
Alai, Hamid [1 ,2 ]
Matanes, Faris N. [1 ,2 ]
Cassidy, Mark M. [1 ,2 ]
Stencel, Jason [1 ,2 ]
Le Jemtel, Thierry H. [1 ,2 ]
机构
[1] Tulane Univ, Med Ctr, Dept Cardiol, 1415 Tulane Ave, New Orleans, LA 70112 USA
[2] Southeast Louisiana Vet Healthcare Syst, 2400 Canal St, New Orleans, LA 70119 USA
来源
关键词
Heart failure with reduced ejection fraction; Acute decompensated heart failure; Decongestion; Diuretics; ANGIOTENSIN-ALDOSTERONE SYSTEM; DIURETIC THERAPY; EJECTION FRACTION; SGLT2; INHIBITORS; MORTALITY; SPIRONOLACTONE; CONGESTION; CARVEDILOL; SODIUM; VOLUME;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Incomplete decongestion is the main cause of readmission in the early post-discharge period of a hospitalization for acute heart failure. Recent heart failure guidelines have highlighted initiation and rapid up-titration of quadruple therapy with angiotensin receptor neprilysin inhibitor, beta adrenergic receptor blocker, mineralocorticoid receptor antagonist, and sodium glucose cotransporter 2 inhibitor to prevent hospitalizations for heart failure with reduced ejection fraction. However, full decongestion remains the foremost therapeutic goal of hospitalization for heart failure. While early addition of sodium glucose cotransporter 2 inhibitors and mineralocorticoid receptor antagonists may be helpful, the value of the other therapeutics comes after decongestion is complete.
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收藏
页码:182 / 189
页数:8
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